Publication List (2021)
非天然骨格を有する新規CERT阻害薬の創成:産学官連携による成果創出
中尾 直樹, 小林 修, 花田 賢太郎
ファルマシア, 57, 1108-1112 (2021). DOI: 10.14894/faruawpsj.57.12_1108
Enantioselective Hydrophosphonylation of N-Boc Imines using Chiral Guanidine–Thiourea Catalysts
L. Chassillan, Y. Yamashita, W.-J. Yoo, M. Toffano, R. Guillot, S. Kobayashi*, G. Vo-Thanh*
Org. Biomol. Chem., 19, 10560-10564 (2021). DOI: 10.1039/D1OB01953H
Silica–Polystyrene Hybrid Core/Shell Microparticles of Rhodium–Chiral Diene Complexes as Catalysts for Asymmetric 1,4-Addition Reactions
T. Kuremoto, R. Sadatsune, T. Yasukawa, S. Kobayashi
ACS Catal., 11, 14026-14031 (2021). DOI: 10.1021/acscatal.1c04539
10 Continuous flow catalysis
H. Ishitani, S. Kobayashi
Volume 1 Flow Chemistry – Fundamentals, 335-378 (2021). DOI: 10.1515/9783110693676-010
Chiral Heterogeneous Scandium Lewis Acid Catalysts for Continuous-Flow Enantioselective Friedel–Crafts Carbon–Carbon Bond-Forming Reactions
Y. Saito, S. Kobayashi*
Angew. Chem. Int. Ed., 60, 26566-26570 (2021). DOI: 10.1002/anie.202112797
Aerobic Dehydrogenative Coupling of Naphthols and Phenols with a Ru(OH)x/Al2O3 Catalyst under Continuous-Flow Conditions
K. Masuda, W. Chen, K. Hayashi, S. Shimada, S. Onozawa,* N. Koumura, K. Sato, S. Kobayashi*
ChemistrySelect, 6, 10106-10110 (2021). DOI: 10.1002/slct.202102938
Development of Trifluoromethanesulfonic Acid-Immobilized Nitrogen-Doped Carbon-Incarcerated Niobia Nanoparticle Catalysts for Friedel–Crafts Acylation
X. Yang, T. Yasukawa*, Y. Yamashita, S. Kobayashi*
J. Org. Chem., 86, 15800-15806 (2021). DOI: 10.1021/acs.joc.1c01944
Two-Step Continuous-Flow Synthesis of Fungicide Metalaxyl through Catalytic C–N Bond-Formation Processes
H. Ishitani*, Z. Yu, T. Ichitsuka, N. Koumura, S. Onozawa, K. Sato, S. Kobayashi*
Adv. Synth. Catal., 364, 18-23 (2021). DOI: 10.1002/adsc.202100898
Recent Advances of Asymmetric Catalysis in Flow for Drug Discovery
Y. Saito, S. Kobayashi*
Top. Med. Chem., 38, 173-222 (2021). DOI: 10.1007/7355_2021_128
Translation of Batch to Continuous Flow in Photoredox Reactions
T. Yasukawa, S. Kobayashi
ACS Cent. Sci., 7, 1099-1101 (2021). DOI: 10.1021/acscentsci.1c00711
Olefination of Aldehydes with Ethyl Diazoacetate Catalyzed by Nitrogen-Doped Carbon-Supported Metal
T. Yasukawa*, S. Kume, Y. Yamashita, S. Kobayashi*
Chem. Lett., 50, 1733-1735 (2021). DOI: 10.1246/cl.210355
α-Alkylation of Ketones with Alkenes Enabled by Photoinduced Activation of Silyl Enol Ethers in the Presence of a Small Amount of Water
T. Hirata, Y. Ogasawara, Y. Yamashita*, S. Kobayashi*
Org. Lett., 23, 5693-5697 (2021). DOI: 10.1021/acs.orglett.1c01824
Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
K. Masuda*, Y. Okamoto, S. Onozawa, N. Koumura, S. Kobayashi*
RSC Adv., 11, 24424-24428 (2021). DOI: 10.1039/D1RA04005G
Machine-Assisted Preparation of a Chiral Diamine Ligand Library and In Silico Screening using Ab Initio Structural Parameters for Heterogeneous Chiral Catalysts
T. Kuremoto, R. Sadatsune, T. Yasukawa, Y. Yamashita, S. Kobayashi*
Adv. Synth. Catal., 363, 4202-4208 (2021). DOI: 10.1002/adsc.202100798
Sequential Continuous-Flow Synthesis of 3-Aryl Benzofuranones
H.-L. Xin, X. Rao, H. Ishitani*, S. Kobayashi*
Chem. Asian J., 16, 1906-1910 (2021). DOI: 10.1002/asia.202100461
Stereoretentive N‐Arylation of Amino Acid Esters with Cyclohexanones Utilizing a Continuous‐Flow System
T. Ichitsuka*, S. Komatsuzaki, K. Masuda, N. Koumura*, K. Sato, S. Kobayashi*
Chem. Eur. J., 27, 10844-10848 (2021). DOI: 10.1002/chem.202101439
Zeolite Catalysis Enables Efficient Pyrazinone Synthesis in Water
T. Hisada, T. Kitanosono*, Y. Yamashita, S. Kobayashi*
Bull. Chem. Soc. Jpn., 94, 1757-1759 (2021). DOI: 10.1246/bcsj.20210112
Synthetic Organic “Aquachemistry” that Relies on Neither Cosolvents nor Surfactants
T. Kitanosono, S. Kobayashi*
ACS Cent. Sci., 7, 739-747 (2021). DOI: 10.1021/acscentsci.1c00045
Chiral Metal Salts as Ligands for Catalytic Asymmetric Mannich Reactions with Simple Amides
Y. Yamashita,* A. Noguchi, S. Fushimi, M. Hatanaka, S. Kobayashi*
J. Am. Chem. Soc., 143, 5598-5604 (2021). DOI: 10.1021/jacs.0c13317
Asymmetric C(sp3)–H functionalization of unactivated alkylarenes such as toluene enabled by chiral Brønsted base catalysts
T. Hirata, I. Sato, Y. Yamashita,* S. Kobayashi*
Commun. Chem., 4, 36 (2021). DOI: 10.1038/s42004-021-00459-5
Nitrogen‐Doped Carbon Enables Heterogeneous Asymmetric Insertion of Carbenoids into Amines Catalyzed by Rhodium Nanoparticles
R. Masuda, T. Yasukawa,* Y. Yamashita, S. Kobayashi*
Angew. Chem., Int. Ed., 60, 12786-12790 (2021). DOI: 10.1002/anie.202102506
Highly Enantioselective Immobilized Prolinamide-Catalyzed Aldol Reactions in Continuous-Flow Systems: Effect of Water on Catalyst Lifetime and Application to the Synthesis of a Chiral Fenpentadiol Analogue
C. Yue, Y. Yamashita,* S. Kobayashi*
Green Chem., 23, 1989-1994 (2021). DOI: 10.1039/D0GC04202A
Zirconium Oxide‐Catalyzed Direct Amidation of Unactivated Esters under Continuous‐Flow Conditions
M. N. Rashed, K. Masuda, T. Ichitsuka, N. Koumura,* K. Sato,* S. Kobayashi*
Adv. Synth. Catal., 363, 2529-2535 (2021). DOI: 10.1002/adsc.202001496
Pt-Catalyzed selective oxidation of alcohols to aldehydes with hydrogen peroxide using continuous flow reactors
Y. Kon*, T. Nakashima, A. Yada, T. Fujitani, S. Onozawa, S. Kobayashi*, K. Sato*
Org. Biomol. Chem., 19, 1115-1121 (2021). DOI: 10.1039/D0OB02213F
High-Throughput Synthesis of (S)-α-Phellandrene through Three-Step Sequential Continuous-Flow Reactions
S. J. Miller, H. Ishitani*, Y. Furiya, S. Kobayashi*
Org. Process Res. Dev., 25, 192-198 (2021). DOI: 10.1021/acs.oprd.0c00391
Well‐Dispersed Trifluoromethanesulfonic Acid‐Treated Metal Oxide Nanoparticles Immobilized on Nitrogen‐Doped Carbon as Catalysts for Friedel–Crafts Acylation
X. Yang, T. Yasukawa*, T. Maki, Y. Yamashita, S. Kobayashi*
Chem. Asian J., 16, 232-236 (2021). DOI: 10.1002/asia.202001274
Hydrogen‐Bonding‐Assisted Cationic Aqua Palladium(II) Complex Enables Highly Efficient Asymmetric Reactions in Water
T. Kitanosono*, T. Hisada, Y. Yamashita, S. Kobayashi*
Angew. Chem., Int. Ed., 60, 3407-3411 (2021). DOI: 10.1002/anie.202009989
New Dimensions of Brønsted Base Catalyzed Carbon–Carbon Bond-Forming Reactions
Y. Yamashita*, S. Kobayashi*
Synlett, 32, 14-22 (2021). DOI: 10.1055/s-0040-1707202
Carbonylative Suzuki–Miyaura Coupling Reactions of Aryl Iodides with Readily Available Polymer-Immobilized Palladium Nanoparticles
T. Yasukawa*, Z. Zhu, Y. Yamashita, S. Kobayashi*
Synlett, 32, 502-504 (2021). DOI: 10.1055/s-0040-1707243