Publication List(2003)

Renaissance of Immobilized Catalysts.  New Types of Polymer-supported Catalysts, “Microencapsulated Catalysts,” which Enable Environmentally Benign and Powerful High-throughput Organic Synthesis,
S. Kobayashi, R. Akiyama,
Chem. Commun., 2003, 449-460.


Ligand-accelerated Cadmium-catalyzed Asymmetric Allylation Reactions in Aqueous Media,
S. Kobayashi, N. Aoyama, K. Manabe,
Chirality
, 15, 124-126 (2003).


Catalytic, Asymmetric Mannich-type Reactions of N-Acylimino Esters.  Reactivity, Diastereo- and Enantioselectivity, and Application to Synthesis of N-Acylated Amino Acid Derivatives,
S. Kobayashi, R. Matsubara, Y. Nakamura, H. Kitagawa, M. Sugiura,
J. Am. Chem. Soc., 125, 2507-2515 (2003).


Hydrophobic Polymer-Supported Catalyst for Organic Reactions in Water: Acid-Catalyzed Hydrolysis of Thioesters and Transprotection of Thiols,
S. Iimura, K. Manabe, S. Kobayashi,
Org. Lett., 5, 101-103 (2003).


Chiral Hetero Diels-Alder Products by Enantioselective and Diastereoselective Zirconium Catalysis.  Scope, Limitation, Mechanism, and Application to Concise Synthesis of (+)-Prelactone C and (+)-9-Deoxygoniopypyrone,
Y. Yamashita, S. Saito, H. Ishitani, S. Kobayashi,
J. Am. Chem. Soc., 125, 3793-3798 (2003).


Platinum-Catalyzed Amidocarbonylation,
T. Sagae, M. Sugiura, H. Hagio, S. Kobayashi,
Chem. Lett., 32, 160-161 (2003).


The Polymer Incarcerated Method for the Preparation of Highly Active Heterogeneous Palladium Catalysts,
R. Akiyama, S. Kobayashi,
J. Am. Chem. Soc., 125, 3412-3413 (2003).


Catalytic Asymmetric Aldol Reactions in Aqueous Media Using Chiral Bis-pyridino-18-crown-6–Rare Earth Metal Triflate Complexes,
T. Hamada, K. Manabe, S. Ishikawa, S. Nagayama, M. Shiro, S. Kobayashi,
J. Am. Chem. Soc., 125, 2989-2996 (2003).


Polymer-Supported Formamides as Reusable Organocatalysts for Allylation of Aldehydes with Allyltrichlorosilane,
C. Ogawa, M. Sugiura, S. Kobayashi,
Chem. Commun., 2003, 192-193.


AgOTf-Catalyzed Aza Diels-Alder Reactions of Danishefsky's Diene with Imines in Water,
C. Loncaric, K. Manabe, S. Kobayashi,
Adv. Synth. Catal., 2003, 475-477.


Microencapsulated Osmium Tetroxide-catalyzed Asymmetric Dihydroxylation of Olefins in Water without Using Any Organic Cosolvents,
T. Ishida, R. Akiyama, S. Kobayashi,
Adv. Synth. Catal., 345, 576-579 (2003).


Lewis Acid-Mediated [3+2] Cycloaddition between Hydrazones and Olefins,
S. Kobayashi, R. Hirabayashi, H. Shimizu, H. Ishitani, Y. Yamashita,
Tetrahedron Lett. 44, 3351-3354 (2003).


Alkaline Salt-Catalyzed Aza Diels-Alder Reactions of Danishefsky's Diene with Imines in Water under Neutral Conditions,
C. Loncaric, K. Manabe, S. Kobayashi,
Chem. Commun., 2003, 574-575.


Allylation Reactions of Carbonyl Compounds Using an Organosilicon Reagent in Aqueous Media,
N. Aoyama, K. Manabe, S. Kobayashi,
Chem. Commun., 2003, 676-677.


Stereoselective Synthesis and Structure-Activity Relationship of Novel Ceramide Trafficking Inhibitors, (1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide (HPA-12) and Its Analogues,
Y. Nakamura, R. Matsubara, H. Kitagawa, S. Kobayashi, K. Kumagai, S. Yasuda, K. Hanada,
J. Med. Chem., 46, 3688-3965 (2003).


Phase-Transfer Alkylation Reactions Using Microreactors,
M. Ueno, H. Hisamoto, T. Kitamori, S. Kobayashi,
Chem. Commun., 2003, 936-937.


Chiral Sulfoxides as Neutral Coordinate-Organocatalysts in Asymmetric Allylation of N-Acylhydrazones Using Allyltrichlorosilanes,
S. Kobayashi, C. Ogawa, H. Konishi, M. Sugiura,
J. Am. Chem. Soc., 125, 6610-6611 (2003).


Mannich-Type Reactions in Water Using a Hydrophobic Polymer-Supported Sulfonic Acid Catalyst,
S. Iimura, D. Nobuto, K. Manabe, S. Kobayashi,
Chem. Commun., 2003, 1644-1645.


The First Catalytic Asymmetric Allylation of Hydrazono Esters in Aqueous Media Using ZnF2–Chiral Diamine,
T. Hamada, K. Manabe, S. Kobayashi, >
Angew. Chem. Int. Ed., 42, 3927-3930 (2003).


Catalytic, Asymmetric Mannich-type Reactions of α-Imino Esters Bearing Readily Removable Substituents on Nitrogen,
Y. Nakamura, R. Matsubara, H. Kiyohara, S. Kobayashi,
Org. Lett., 5, 2481-2484 (2003).


An Air-Stable, Storable Chiral Zirconium Catalyst for Asymmetric Aldol Reactions,
S. Kobayashi, S. Saito, M. Ueno, Y. Yamashita,
Chem. Commun., 2003, 2016-2017.


Mechanistic Studies on the Catalytic Cycle of Metal Fluoride-Catalyzed Allylation Using Allyltrimethoxysilane in Protic Solvents,
N. Aoyama, K. Manabe, S. Kobayashi,
J. Org. Chem., 68, 7329-7333 (2003).


Hydrophobic, Low-Loading and Alkylated Polystyrene-Supported Sulfonic Acid for Several Organic Reactions in Water: Remarkable Effects of Both the Polymer Structures and Loading Levels of Sulfonic Acids,
S. Iimura, K. Manabe, S. Kobayashi,
Org. Biomol. Chem., 1, 2416-2418 (2003).


Chemistry and Biology of Khafrefungin. Large-Scale Synthesis, Design, and Structure–Activity Relationship of Khafrefungin, an Antifungal Agent,
M. Nakamura, Y. Mori, K. Okuyama, K. Tanikawa, S. Yasuda, K. Hanada, S. Kobayashi,
Org. Biomol. Chem., 1, 3362-3376 (2003).


Lewis Acid-Catalyzed Asymmetric Hydroxymethylation of Silicon Enolates in Aqueous Media,
K. Manabe, S. Ishikawa, T. Hamada, S. Kobayashi,
Tetrahedron, 59, 10439-10444 (2003).


Radical-mediated Carbonylation of Alkyl Iodides in Aqueous Media,
M. Sugiura, H. Hagio, S. Kobayashi,
Chem. Lett., 32, 898-899 (2003).


Mannich-Type Reactions Catalyzed by Neutral Salts in Water,
C. Loncaric, K. Manabe, S. Kobayashi,
Adv. Synth. Catal., 345, 1187-1189 (2003).


Palladium-Catalyzed, Carboxylic Acid-Assisted Allylic Substitution of Carbon Nucleophiles with Allyl Alcohols as Allylating Agents in Water,
K. Manabe, S. Kobayashi,
Org. Lett., 5, 3241-3244 (2003).


The First Allylation of Imines with Allyltrichlorosilanes Using Neutral Coordinate-Organocatalysts,
M. Sugiura, F. Robvieux, S. Kobayashi,
Synlett, 2003, 1749-1751.


Catalytic Deprotection of Protected Alcohols in Water Using Low-Loading and Alkylated Polystyrene-Supported Sulfonic Acid,
S. Iimura, K. Manabe, S. Kobayashi,
J. Org. Chem., 68, 8723-8725 (2003).