Our paper "Sequential-Flow Synthesis of Donepezil: A Green and Sustainable Strategy Featuring Heterogeneous Catalysis and Hydrogenation" was published in
Chem. Eur. J..
September, 2nd, 2024 New!
Our paper "TEMPO-Catalyzed Continuous-flow Aerobic Oxidations of Alcohols on Silica" was published in
ChemCatChem.
August, 17th, 2024 New!
Our paper "Vigorously Stirred La2O3 Suspensions for Michael Additions in Water" was published in
Chem. Commun..
Our paper "Small-Molecule-Based Strategy for Mitigating Deactivation of Chiral Lewis Acid Catalysis" was published in
J. Am. Chem. Soc..
June, 26th, 2024 New!
Our paper "Direct Aromatic Nitrosation Using 2-Methoxyethyl Nitrite as a NO Cation Source" was published in
Org. Lett..
June, 25th, 2024 New!
Our paper "Continuous-flow Directed C–H Amidation Reactions Using Immobilized Cp*Rh(III) Catalysts" was published in
Green Chem..
June, 24th, 2024
Our paper "Selective Hydrogenation of Quinizarins to Leuco-quinizarins and Their Direct Derivatization Using Flow-Batch-Separator Unified Reactors under Continuous-Flow Conditions" was published in
ACS Catal..
June, 20th, 2024
Our paper "Catalytic Activation of Bis(2,2,2-trifluoroethyl) phosphite with Hf(IV) for the Synthesis of Mixed Dialkyl Phosphites" was published in
Adv. Synth. Catal..
An editorial issue "Flow Chemistry and Continuous Processing: More Mainstream than Ever!" was published in
Org. Process Res. Dev..
May, 6th, 2024
Our paper "Nanoscale and chiral metal–organic frameworks for asymmetric reactions in water: bridging Lewis acid catalysis and biological systems" was published in
Chem. Sci..
April, 26th, 2024
Our review "Efficient Radical-mediated Intermolecular α-Alkylation Reactions of Carbonyl Compounds with Nonactivated Alkenes" was published in
Chem. Asian J..
April, 26th, 2024
Our paper "Reductive N-Alkylation of Amines with Ketones Using Heterogeneous Polysilane–Palladium Catalysts under Continuous-Flow Conditions" was published in
Org. Lett..
Our paper "A Highly Efficient Catalytic Method for the Synthesis of Phosphite Diesters" was published in
Chem. Sci..
February, 19th, 2024
Our paper "Development of Catalytic Enantioselective Mannich Reactions Using Esters" was published in
Org. Lett..
February, 8th, 2024
Our paper "Continuous Synthesis of Homoallylic Ketones via Ketal–Claisen Rearrangement using Solid-Acid Catalysts" was published in
Org. Chem. Front..
January, 26th, 2024
Our paper "Continuous-Flow Enantioselective Hydrogenative Enyne Cyclization with Chiral Heterogeneous Rh Catalysts" was published in
ACS Catal..
January, 18th, 2024
Our paper "Enantioselective Acyl-Transfer/Protonation Reactions with Newly Designed Chiral Thiourea-Iminophosphorane Catalysts" was published in
Adv. Synth. Catal..
January, 13th, 2024
Our paper "Water vs. Organic Solvents: Water-Controlled Divergent Reactivity of 2-Substituted Indoles" was published in
Chem. Asian J..
January, 12th, 2024
Our paper "Continuous-Flow Asymmetric Hydrogenation for the Synthesis of an (S)-Metolachlor Intermediate Using Catalysts Immobilized on a Core/Shell-Type Support" was published in
Adv. Synth. Catal..
Our paper "Continuous-Flow Enantioselective Hydroacylations under Heterogeneous Chiral Rhodium Catalysts" was published in
Angew. Chem. Int. Ed..
November, 20th, 2023
Our paper "Development of Photoredox-assisted Direct a-Alkylation Reactions of Ketones with Arylalkenes using a Catalytic Amount of LiO t Bu as a Brønsted Base" was published in
Helv. Chim. Acta.
October, 17th, 2023
Our paper "Photoinduced Efficient Catalytic α-Alkylation Reactions of Active Methylene and Methine Compounds with Nonactivated Alkenes" was published in
J. Am. Chem. Soc..
September, 6th, 2023
Our paper "Highly enantioselective hydroxymethylation of unmodified α-substituted aryl ketones in water" was published in
Proc. Jpn. Acad., Ser. B.
September, 5th, 2023
Our paper "Aluminium-catalysed synthesis of aryl enol ethers from phenols and dimethyl ketals" was published in
Org. Biomol. Chem..
August, 29th, 2023
Our paper "Continuous-flow dehydrative amidation between carboxylic acids and amines using modified mixed metal oxides as solid acid catalysts" was published in
Catal. Sci. Technol..
August, 18th, 2023
Our paper "Bead Mill-Driven Acceleration of Catalytic Methanolysis of Poly(ethylene terephthalate) under Mild Reaction Conditions" was published in
Chem. Lett..
Our paper "A Practical and Convenient Synthesis of the Essential Antibiotic Drug Cefazolin under Sequential One-Flow Conditions" was published in
Bull. Chem. Soc. Jpn..
Prof. Shū Kobayashi, Proj. Prof. Haruro Ishitani, and Dr. Shoichi Sugita recieved the BCSJ Award Article for this paper.
August, 2nd, 2023
Our paper "Continuous-flow Reductive N-Methylation with Highly Active Heterogeneous Pd Catalysts and Sequential-flow Synthesis of N-Monomethyl Amines" was published in
Green Chem..
July, 11th, 2023
Our paper "A Chronicle of Organic Synthesis in Water: A Trajectory of Growth in the Intervening Quarter Century" was published in
Tetrahedron.
June, 23rd, 2023
Our paper "Continuous Synthesis of Epoxides from Alkenes by Hydrogen Peroxide with Titanium Silicalite-1 Catalyst Using Flow Reactors" was published in
Adv. Synth. Catal.
May, 25th, 2023
Our paper "Heterogeneous Single-Atom Zinc on Nitrogen-Doped Carbon Catalyzed Electrochemical Allylation of Imines" was published in
J. Am. Chem. Soc.
May, 8th, 2023
Our paper "A Continuous-Flow Method for the Transformation from Amides to Nitriles Catalyzed by CeO2 in Acetonitrile" was published in
Adv. Synth. Catal.
May, 8th, 2023
Our paper "Catalytic hydrogenative dechlorination reaction for efficient synthesis of a key intermediate of SDHI fungicides under continuous-flow conditions" was published in
Catal. Sci. Technol.
Our paper "Liquid-phase Catalytic Continuous-Flow Aromatic Nitration Reactions with Conc. HNO3 on Modified Mixed-Metal Oxide Composites as High-Yielding Solid Acid Catalysts" was published in
ACS Sus. Chem. Eng.
March, 29th, 2023
Our paper "Continuous-Flow Enantioselective 1,4-Addition Reactions of Malonates with Nitroolefins on Ni-Supported Mesoporous Silica Materials with Co-feeding of a Chiral Ligand" was published in
Adv. Synth. Catal.
December, 16th, 2022
Ph.D. thesis of Proj. Asst. Prof. Yuki Saito has been published as a book.
November, 29th, 2022
Our paper "Development of Metal-Free, Trifluoromethanesulfonic Acid-Immobilized Nitrogen-Doped Carbon Catalysts for Povarov Reactions" was published in
J. Org. Chem..
October, 7th, 2022
A miniature of our laboratory's equipment was exhibited in the Science Gallery. Click here for the introduction
September, 29th, 2022
Our paper "Effect of Activation Methods of Molecular Sieves on Ketimine Synthesis" was published in
J. Org. Chem..
August, 31st, 2022
Our paper "Continuous-flow Oxidation of Alcohols" was published in
Adv. Synth. Catal..
August, 29th, 2022
Our paper "Continuous-flow Diels-Alder Reactions of Unactivated Dienes over Zeolitic Catalysts" was published in
Asian J. Org. Chem..
August, 15th, 2022
Our paper "Continuous-Flow Synthesis of β-Ketoesters" was published in
Adv. Synth. Catal..
July, 25th, 2022
Our paper "Photocatalytic Addition Reactions of Ketene Silyl Acetals with Alkenes" was published in
Chem. Asian J..
July, 16th, 2022
Our paper "Hydrogen generation from organic hydride under continuus-flow conditions" was published in
Chem. Asian J..