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Synthesis of Bioactive Compounds

 As a practical applied example of a catalyst and the reaction system which we developed, we synthesized various bioactive compounds. As for most of these compounds, the configuration of structure was unclear when we began the synthesis. Asymmetric synthesis can produce any stereoisomers. Therefore, we could determine the actual configurations of these compounds or found the error of reported structure, at the same time finish the total synthesis.


  1. Revised Stereochemistry of Ceramide-Trafficking Inhibitor HPA-12 by X-ray Crystallography Analysis