Publication List(2001)

A Novel Chiral Zirconium Catalyst for Enantioselective Aldol and Mannich-type Reactions. Catalytic Activation of Both Aldehydes and Imines Using a Similar Chiral Lewis Acid,
S. Kobayashi, H. Ishitani, Y. Yamashita, M. Ueno, H. Shimizu,
, 57, 861-866 (2001).

Three-component Carbon-Carbon Bond-forming Reactions Catalyzed by a Brønsted acid-Surfactant-combined Catalyst in Water,
K. Manabe, Y. Mori, S. Kobayashi,
Tetrahedron Lett.
, 57 , 2537-2544 (2001).

Catalytic Friedel-Crafts Acylation of Aniline Derivatives,
S. Kobayashi, I. Komoto, J.-i. Matsuo,
Adv. Synth. Catal.
, 343, 71-74 (2001).

Efficient Synthesis of Piperidine Derivatives.  Development of Metal Triflate-Catalyzed Diastereoselective Nucleophilic Substitution Reactions of 2-Methoxy- and 2-Acyloxypiperidines,
O. Okitsu, R. Suzuki, S. Kobayashi,
J. Org. Chem.
, 66, 809-823 (2001).

Polymer-Supported Glyoxylate and α-Imino Acetates.  Versatile Reagents for the Synthesis of α-Hydroxycarboxylic Acid and α-Amino Acid Libraries,
S. Kobayashi, R. Akiyama, H. Kitagawa,
J. Combi. Chem.
, 3, 196-204 (2001).

Total Synthesis and Structural Elucidation of Khafrefungin,
T. Wakabayashi, K. Mori, S. Kobayashi,
J. Am. Chem. Soc.
, 123, 1372-1375 (2001).

Friedel-Crafts-type Conjugate Addition of Indoles Using a Lewis Acid-Surfactant-combined Catalyst in Water,
K. Manabe, N. Aoyama, S. Kobayashi,
Adv. Synth. Catal.
, 343, 174-176 (2001).

Lanthanide Trifluoromethanesulfonate-catalyzed Asymmetric Aldol Reactions in Aqueous Media,
S. Kobayashi, T. Hamada, S. Nagayama, K. Manabe,
Org. Lett.
, 3, 165-167 (2001).

Scandium Perfluoroalkanesulfonate-catalyzed Diels-Alder Reactions in an Organic Solvent,
S. Kobayashi, T. Tsuchiya, I. Komoto, J.-i. Matsuo,
J. Organomet. Chem.
, 624, 392-394 (2001).

Highly Enantioselective Allylation of Imines Using a Novel Chiral Zirconium Catalyst,
T. Gastner, H. Ishitani, R. Akiyama, S. Kobayashi,
Angew. Chem. Int. Ed.,
40, 1896-1898 (2001).

Lewis Acid-catalyzed Ring-Opening Reactions of Semicyclic N,O-Acetals,
M. Sugiura, S. Kobayashi,
Org. Lett.
, 3, 477-480 (2001).

A Ligand-accelerated Chiral Lewis Acid Catalyst in Asymmetric Michael Addition of Thiols to α,&beta-Unsaturated Carbonyls,
S. Kobayashi, C. Ogawa, M. Kawamura, M. Sugiura,
, 2001, 983-985.

Direct Formation of N-Acylated Amino Acid Derivatives via Nucleophilic Addition to N-Acylimino Esters Using a Polymer-supported Amine and Scandium Triflate,
S. Kobayashi, H. Kitagawa, R. Matsubara,
J. Combi. Chem.
, 3, 401-403 (2001).

Catalytic Use of a Boron Source for Boron Enolate-mediated Stereoselective Aldol Reactions in Water,
Y. Mori, K. Manabe, S. Kobayashi,
Angew. Chem. Int. Ed.
, 40, 2815-2818 (2001).

Lewis Acid-catalyzed Allylation Reactions of Acylhydrazones with Tetraallyltin in Aqueous Media,
S. Kobayashi, T. Hamada, K. Manabe,
, 2001, 1140-1142.

Microencapsulated Palladium Catalysts. Allylic Substitution and Suzuki Coupling Using a Recoverable and Reusable Polymer-supported Palladium Catalyst,
R. Akiyama, S. Kobayashi,
Angew. Chem. Int. Ed.
, 40, 3469-3471 (2001).

Highly Stereoselective Synthesis of Homoallylic Amines Based on Addition of Allyltrichlorosilanes to Benzoylhydrazones,
R. Hirabayashi, C. Ogawa, M. Sugiura, S. Kobayashi,
J. Am. Chem. Soc.
, 123, 9493-9499 (2001).

Ring-opening Allylation of Semicyclic N,O-Acetals Catalyzed by a Lewis Acid,
>M. Sugiura, H. Hagio, R. Hirabayashi, S. Kobayashi,
, 2001, 1225-1228.

Convergent Total Synthesis of Khafrefungin and Its Inhibitory Activity of Fungal Sphingolipids Syntheses,
S. Kobayashi, K. Mori, T. Wakabayashi, S. Yasuda, K. Hanada,
J. Org. Chem.
, 66, 5580-5584 (2001).

Catalytic Asymmetric Dihydroxylation Using Phenoxyethoxymethyl-polystyrene (PEM)-based Novel Microencapsulated Osmium Tetroxide (PEM-MC OsO4),
S. Kobayashi, T. Ishida, R. Akiyama,
Org. Lett.
, 3, 2649-2652 (2001).

A Novel Inhibitor of Ceramide Trafficking from Endoplasmic Reticulum to the Site of Sphingomyelin Synthesis,
S. Yasuda, H. Kitagawa, M. Ueno, H. Ishitani, M. Fukasawa, M. Nishijima, S. Kobayashi, K. Hanada,
J. Biol. Chem.
, 276, 43994-44002 (2001).

Dehydration Reactions in Water. Surfactant-type Brønsted Acid-catalyzed Direct Esterification of Carboxylic Acids with Alcohols in an Emulsion System,
K. Manabe, X.-M. Son, S. Kobayashi,
J. Am. Chem. Soc.
, 123, 10101-10102 (2001).

Asymmetric Catalysis in Aqueous Media: Use of Metal-Chiral Crown Ethers as Efficient Chiral Lewis Acid Catalysts in Asymmetric Aldol Reactions,
S. Kobayashi, T. Hamada, S. Nagayama, K. Manabe,
J. Braz. Chem. Soc., 12, 627-633 (2001).

Lewis Acid Catalysis in a Supercritical Carbon Dioxide (scCO2)-Poly(ethylene glycol) Derivatives (PEGs) System: Remarkable Effect of PEGs as Additives on Reactivity of Ln(OTf)3-catalyzed Mannich and Aldol Reactions in scCO2,
I. Komoto, S. Kobayashi,
Chem. Commun.
, 2001, 1842-1843.

Asymmetric Synthesis of Proline and Pipecolic Acid Phosphorous Analogues Using Enantioselective Deprotonation-carboxylation Reactions,
S. Kobayashi, N. Shiraishi, W. W.-L. Lam, K. Manabe,
Tetrahedron Lett.
, 42, 7303-7306 (2001).

New Methods for High-throughput Synthesis,
S. Kobayashi, R. Akiyama,
Pure Appl. Chem.
, 73, 1103-1111 (2001).

Catalytic Enantioselective Synthesis of a Novel Inhibitor of Ceramide Trafficking, (1R, 3R)-N-(3-hydroxy-1-hydroxymethy1-3-phenylpropyl)-dodecanamide (HPA-12),
M. Ueno, H. Kitagawa, H. Ishitani, S. Yasuda, K. Hanada, S. Kobayashi,
Tetrahedron Lett.
, 42, 7863-7865 (2001).

Lewis Acid-Catalyzed Ring-Opening Reactions of Semicyclic N,O-Acetals Possessing an Exocyclic Nitrogen Atom: Mechanistic Aspect and Application to Piperidine Alkaloid Synthesis,
M. Sugiura, H. Hagio, R. Hirabayashi, S. Kobayashi,
J. Am. Chem. Soc.
, 123, 12510-12517 (2001).

Chiral Lewis Acid-Catalyzed Enantioselective Michael Reactions in Water,
S. Kobayashi, K. Kakumoto, Y. Mori, K. Manabe,
Israel J. Chem.
, 41, 247-249 (2001).