Xiyun Ye

Postdoctoral researcher

City/country of origin
Running, piano, hiking, and reading
Places You Like
Ocean beach
Where for a big vacation
Music: what is some intense music for intense lab work?
What are people in the lab doing?
What was surprising about the suga lab
So many instruments
Original motivation towards science?
A few words for future lab mates
Have fun :D
Science is…….
Challenging and fun

Education & professional career

Massachusetts Institute of Technology- PhD
University of Chicago
University of Hong Kong


"Synthesis of proteins by automated flow chemistry."
N. Hartrampf; A. Saebi; M. Poskus; Z.P. Gates; A.J. Callahan; A.E. Cowfer; S. Hanna; S. Antilla; C.K. Schissel; A.J. Quartararo; X. Ye; A.J. Mijalis; M.D. Simon; A. Loas; S. Liu; C. Jessen; T.E. Nielsen; B.L. Pentelute
Science, 368, 980-987 (2020)
"De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein."
S. Pomplun; M. Jbara; A.J. Quartararo; G. Zhang; J.S. Brown; Y.C. Lee; X. Ye; S. Hanna; B.L. Pentelute
ACS Cent Sci, 7, 156-163 (2021)
"Ultra-large chemical libraries for the discovery of high-affinity peptide binders."
A.J. Quartararo; Z.P. Gates; B.A. Somsen; N. Hartrampf; X. Ye; A. Shimada; Y. Kajihara; C. Ottmann; B.L. Pentelute
Nat Commun, 11, 3183 (2020)
"Binary combinatorial scanning reveals potent poly-alanine-substituted inhibitors of protein-protein interactions."
X. Ye; Y.C. Lee; Z.P. Gates; Y. Ling; J.C. Mortensen; F.S. Yang; Y.S. Lin; B.L. Pentelute
Commun Chem, 5, 128 (2022)
"Branched Multimeric Peptides as Affinity Reagents for the Detection of alpha-Klotho Protein."
X. Ye; P. Zhang; J.C.K. Wang; C.L. Smith; S. Sousa; A. Loas; D.L. Eaton; M. Preciado Lopez; B.L. Pentelute
Angew Chem Int Ed Engl, 62, e202300289 (2023)

Contact info

    • E-mail… xiyunye"at"g.ecc.u-tokyo.ac.jp (change "at" to @)