陶慧Hui Tao

Postdoctoral Fellow


City/country of origin
Hunan, China
Hobbies
Traveling and Cooking
Places You Like
Home town, Coffee bar, and seaside
Where for a big vacation
Ice land, Southern Europe
What are your strong points?
Perseverance, Good Listener
Music: what is some intense music for intense lab work?
I normally work without music...
What are people in the lab doing?
Great and happy researches
What was surprising about the suga lab
Diverse and flexible
Original motivation towards science?
Just followed my heart
A few words for future lab mates
Good luck!
Science is…….
Something we don't know yet

学歴・職歴

2009-2013
B.Sc., Pharmacy, Wuhan University, Supervisor: Prof. Tiangang Liu
2013-2018
Ph.D., Biochemistry and Molecular Biology, Wuhan University, Supervisor: Prof. Zixin Deng
2018-2022
Postdoctoral Fellow, Synthetic Biology, The University of Tokyo, Supervisor: Prof. Ikuro Abe
2022-present
Postdoctoral Fellow, Bioorganic Chemistry, The University of Tokyo, Supervisor: Prof. Hiroaki Suga

発表論文

"Molecular insights into the unusually promiscuous and catalytically versatile Fe (II)/α-ketoglutarate-dependent oxygenase SptF."
H. Tao; T. Mori; H. Chen; S. Lyu; A. Nonoyama; S. Lee; I. Abe
Nature communications, 13, 1-13 (2022)
"Discovery of non-squalene triterpenes."
H. Tao; L. Lauterbach; G. Bian; R. Chen; A. Hou; T. Mori; S. Cheng; B. Hu; L. Lu; X. Mu
Nature, 1-6 (2022)
"Harnessing Fe (II)/α-ketoglutarate-dependent oxygenases for structural diversification of fungal meroterpenoids."
H. Tao; I. Abe
Current Opinion in Biotechnology, 77, 102763 (2022)
"Rational Engineering of the Nonheme Iron-and 2-Oxoglutarate-Dependent Oxygenase SptF."
T. Mori; Z. Yu; H. Tao; I. Abe
Organic Letters, 24, 1737-1741 (2022)
"One Polyketide Synthase, Two Distinct Products: Trans‐Acting Enzyme‐Controlled Product Divergence in Calbistrin Biosynthesis."
H. Tao; T. Mori; X. Wei; Y. Matsuda; I. Abe
Angewandte Chemie International Edition, 60, 8851-8858 (2021)
"Enzymology and biosynthesis of the orsellinic acid derived medicinal meroterpenoids."
H. Tao; I. Abe
Current Opinion in Biotechnology, 69, 52-59 (2021)
"Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton."
Z. An; H. Tao; Y. Wang; B. Xia; Y. Zou; S. Fu; F. Fang; X. Sun; R. Huang; Y. Xia
Synthetic and systems biotechnology, 6, 292-301 (2021)
"Structural diversification of andiconin-derived natural products by α-ketoglutarate-dependent dioxygenases."
T. Bai; Y. Matsuda; H. Tao; T. Mori; Y. Zhang; I. Abe
Organic Letters, 22, 4311-4315 (2020)
"Strategies for enhancing the yield of the potent insecticide spinosad in actinomycetes."
H. Tao; Y. Zhang; Z. Deng; T. Liu
Biotechnology journal, 14, 1700769 (2019)
"Heterologous biosynthesis of spinosad: an omics-guided large polyketide synthase gene cluster reconstitution in Streptomyces."
G.-Y. Tan; K. Deng; X. Liu; H. Tao; Y. Chang; J. Chen; K. Chen; Z. Sheng; Z. Deng; T. Liu
ACS Synthetic Biology, 6, 995-1005 (2017)
"Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6."
G. Bian; Y. Yuan; H. Tao; X. Shi; X. Zhong; Y. Han; S. Fu; C. Fang; Z. Deng; T. Liu
Biotechnology Journal, 12, 1600697 (2017)
"Absolute quantification of proteins in the fatty acid biosynthetic pathway using protein standard absolute quantification."
H. Tao; Y. Zhang; X. Cao; Z. Deng; T. Liu
Synthetic and systems biotechnology, 1, 150-157 (2016)
"Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property."
H. Tao; D. Guo; Y. Zhang; Z. Deng; T. Liu
Biotechnology for biofuels, 8, 1-11 (2015)

連絡先

    • E-mail… thui@(@以下はg.ecc.u-tokyo.ac.jp)