陶慧Hui Tao
Postdoctoral Fellow
- City/country of origin
- Hunan, China
- Hobbies
- Traveling and Cooking
- Places You Like
- Home town, Coffee bar, and seaside
- Where for a big vacation
- Ice land, Southern Europe
- What are your strong points?
- Perseverance, Good Listener
- Music: what is some intense music for intense lab work?
- I normally work without music...
- What are people in the lab doing?
- Great and happy researches
- What was surprising about the suga lab
- Diverse and flexible
- Original motivation towards science?
- Just followed my heart
- A few words for future lab mates
- Good luck!
- Science is…….
- Something we don't know yet
学歴・職歴
- 2009-2013
- B.Sc., Pharmacy, Wuhan University, Supervisor: Prof. Tiangang Liu
- 2013-2018
- Ph.D., Biochemistry and Molecular Biology, Wuhan University, Supervisor: Prof. Zixin Deng
- 2018-2022
- Postdoctoral Fellow, Synthetic Biology, The University of Tokyo, Supervisor: Prof. Ikuro Abe
- 2022-present
- Postdoctoral Fellow, Bioorganic Chemistry, The University of Tokyo, Supervisor: Prof. Hiroaki Suga
発表論文
- "Molecular insights into the unusually promiscuous and catalytically versatile Fe (II)/α-ketoglutarate-dependent oxygenase SptF."
- H. Tao; T. Mori; H. Chen; S. Lyu; A. Nonoyama; S. Lee; I. Abe
- Nature communications, 13, 1-13 (2022)
- "Discovery of non-squalene triterpenes."
- H. Tao; L. Lauterbach; G. Bian; R. Chen; A. Hou; T. Mori; S. Cheng; B. Hu; L. Lu; X. Mu
- Nature, 1-6 (2022)
- "Harnessing Fe (II)/α-ketoglutarate-dependent oxygenases for structural diversification of fungal meroterpenoids."
- H. Tao; I. Abe
- Current Opinion in Biotechnology, 77, 102763 (2022)
- "Rational Engineering of the Nonheme Iron-and 2-Oxoglutarate-Dependent Oxygenase SptF."
- T. Mori; Z. Yu; H. Tao; I. Abe
- Organic Letters, 24, 1737-1741 (2022)
- "One Polyketide Synthase, Two Distinct Products: Trans‐Acting Enzyme‐Controlled Product Divergence in Calbistrin Biosynthesis."
- H. Tao; T. Mori; X. Wei; Y. Matsuda; I. Abe
- Angewandte Chemie International Edition, 60, 8851-8858 (2021)
- "Enzymology and biosynthesis of the orsellinic acid derived medicinal meroterpenoids."
- H. Tao; I. Abe
- Current Opinion in Biotechnology, 69, 52-59 (2021)
- "Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton."
- Z. An; H. Tao; Y. Wang; B. Xia; Y. Zou; S. Fu; F. Fang; X. Sun; R. Huang; Y. Xia
- Synthetic and systems biotechnology, 6, 292-301 (2021)
- "Structural diversification of andiconin-derived natural products by α-ketoglutarate-dependent dioxygenases."
- T. Bai; Y. Matsuda; H. Tao; T. Mori; Y. Zhang; I. Abe
- Organic Letters, 22, 4311-4315 (2020)
- "Strategies for enhancing the yield of the potent insecticide spinosad in actinomycetes."
- H. Tao; Y. Zhang; Z. Deng; T. Liu
- Biotechnology journal, 14, 1700769 (2019)
- "Heterologous biosynthesis of spinosad: an omics-guided large polyketide synthase gene cluster reconstitution in Streptomyces."
- G.-Y. Tan; K. Deng; X. Liu; H. Tao; Y. Chang; J. Chen; K. Chen; Z. Sheng; Z. Deng; T. Liu
- ACS Synthetic Biology, 6, 995-1005 (2017)
- "Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6."
- G. Bian; Y. Yuan; H. Tao; X. Shi; X. Zhong; Y. Han; S. Fu; C. Fang; Z. Deng; T. Liu
- Biotechnology Journal, 12, 1600697 (2017)
- "Absolute quantification of proteins in the fatty acid biosynthetic pathway using protein standard absolute quantification."
- H. Tao; Y. Zhang; X. Cao; Z. Deng; T. Liu
- Synthetic and systems biotechnology, 1, 150-157 (2016)
- "Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property."
- H. Tao; D. Guo; Y. Zhang; Z. Deng; T. Liu
- Biotechnology for biofuels, 8, 1-11 (2015)
連絡先
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- E-mail… thui@(@以下はg.ecc.u-tokyo.ac.jp)