2014年
2013年
2012年
2011年
2010年
2009年
2008年
2007年
2006年
2005年
2004年
2003年
2002年
2001年
2000年
1999年
1998年
1997年
1996年
1991-1995年
conference
著作

業績

2014年

Suzuki, R.; Irie, R.; Harntaweesup, Y.; Tachibana, K.; Holland, P. T.; Harwood, T. D.; Shi, F.; Beuzenberg, V.; Itoh, Y.; Pascal, S; Edwards, P. J. B; Satake, M.
"Brevisulcatic Acids, Marine Ladder-Frame Polyethers from the Red Tide Dinoflagellate Karenia brevisulcata in New Zealand"
Org. Lett., 16(22), 5850-5853 (2014)

Inoue, H.; Hidaka, D.; Fukuzawa, S.; Tachibana, K.
"Truncated norzoanthamine exhibiting similar collagen protection activity, toward a promising anti-osteoporotic drug"
Bioorg. Med. Chem. Lett., 24, 508-509 (2014)

Tomohiro Shirai, Yuki Takimoto, Takefumi Kuranaga, Kazuo Tachibana, Masayuki Satake, Daniel G. Baden, and Jeffrey L. C. Wright
"Synthesis and Cyclization of a Proposed Biosynthetic Epoxy Intermediate of a Marine Monocyclic Ether Amide, Brevisamide"
HeteroCycles., 89, 127-142 (2014)

Inoue, H.; Tokita, K.; Fukuzawa, S.; Tachibana, K.
"Structure-activity relationships of the truncated norzoanthamines exhibiting collagen protection toward anti-osteoporotic activity. "
Bioorg. Med. Chem., 22, 3455-3464 (2014)

Yamada, K.; Kuriyama, H.; Hara, T.; Murata, M.; Irie, R.; Harntaweesup, Y.; Satake, M.; Fukuzawa, S.; Tachibana, K.
"Interaction analysis of a ladder-shaped polycyclic ether and model transmembrane peptides in lipid bilayers by using Forster resonance energy transfer and polarized attenuated total reflection infrared spectroscopy. "
Bioorg. Med. Chem., 22, 3773-3780 (2014)

2013年

Ryuichi Watanabe, Hajime Uchida, Toshiyuki Suzuki, Ryoji Matsushima, Mika Nagae, Yoshikazu Toyohara, Masayuki Satake, Yasukatsu Oshima, Akio Inoue, Takeshi Yasumoto
"Gambieroxide, a novel epoxy polyether compound from the dinoflagellate Gambierdiscus toxicus GTP2 strain"
Tetrahedron., 69, 10299-10303 (2013)

Yoshihisa Tanaka, Masayuki Satake,* Mari Yotsu-Yamashita, and Yasukatsu Oshima
"GYMNOCIN-A CARBOXYLIC ACID AND GYMNOCIN-A2, CYTOTOXIC POLYETHERS FROM THE RED TIDE DINOFLAGELLATE KARENIA MIKIMOTOI"
HeteroCycles, 87, 2037-2046(2013)

2012年

Yamazaki, M.; Izumikawa, M.; Tachibana, K.; Satake, M.; Itoh, Y.; Hashimoto, M.
"Origins of Oxygen Atoms in A Marine Ladder-Frame Polyether: Evidence of Monooxygenation by 18O-Labeling and Using Tandem Mass Spectrometry"
J. Org. Chem., 77, 4902-4906 (2012)

Yoshinaka-Niitsu, A.; Yamagaki, T.; Harada, M.; Tachibana, K.
"Solution NMR analysis of the binding mechanism of DIVS6 model peptides of voltage-gated sodium channels and the lipid soluble alkaloid veratridine"
Bioorg. Med. Chem., 20, 2796-2802 (2012)

Hamamoto, Y.; Tachibana, K; Holland, T. P.; Shi, F.; Beuzenberg, V.; Itoh, Y.; Satake, M.
"Brevisulcenal-F: A polycyclic Ether Toxin Associated with Massive Fishkills in New Zealand"
J. Am. Chem. Soc., 134, 4963-4968 (2012)

Holland, T. P.; Shi, F.; Satake, M.; Hamamoto, Y.; Ito, E.; Beuzenberg, V.; Mcnabb, P.;Mundey, R.; Briggs, L.; Truman, P.; Gooneratne, R; Edwards, P.; Pascal, M. S.
"Novel toxins produced the dinoflagellate Karenia brevisulcata"
Harmful Algae 13, 47-57 (2012)

2011年

Sugahara, K.; Kitamura, Y.; Murata, M.; Satake, M.; Tachibana, K.
"Prorocentrol, a Polyoxy Linear Carbon Chain Compound Isolated from the Toxic Dinoflagellate Prorocentrum hoffmannianum"
J. Org. Chem. 76, 3131-3138 (2011)

Kuranaga, T.; Ohtani, N.; Tsutsumi, R.; Baden, D. G.; Wright, J. L. C.; Satake, M.; Tachibana, K.
"Total Synthesis of (-)-Brevisin: A Concise Syntheis of a New Marine Polycyclic Ether"
Organic Letters 13, 696-699 (2011)

Yamazaki, M.; Tachibana, K.; Satake, M.
"Complete 13C-labeling pattern of yessotoxin a marine ladder-frame polyether"
Tetrahedron 67, 877-880 (2011)

2010年

Kuranaga, T.; Ishihara, S.; Ohtani, N.; Satake, M.; Tachibana, K.
"Chemoselective deprotection of silyl ethers by DIBALH"
Tetrahedron Letters 51, 6345-6348 (2010)

Kuranaga, T.; Satake, M.; Baden, D. G.; Wright, J. L. C.; Tachibana, K.
"Synthesis of the BC/DE ring model of brevisin for confirmation of the structure around the acyclic junction"
Tetrahedron Letters 51, 4673-4676 (2010)

Tsutsumi, R.; Kuranaga, T.; Wright, J.L.C.; Baden, D. G.; Ito, E.; Satake, M.; Tachibana, K.
"An improved synthesis of (-)-brevisamide, a marine monocyclic ether amide of dinoflagellate origin"
Tetrahedron 66, 6775-6782 (2010)

Ohtani, N.; Tsutsumi, R.; Kuranaga, T.; Shirai, T.; Wright, J. L. C.; Baden, D. G.; Satake M.; Tachibana K.
"Synthesis of the ABC Ring Fragment of Brevisin, a New Dinoflagellate Polycyclic Ether"
Heterocycles 80, 825-830 (2010)

Genji, T.; Fukuzawa, S.; Tachibana, K.
"Distribution and possible function of the marine alkaloid, norzoanthamine, in the zoanthid Zoanthus sp. using MALDI imaging mass spectrometry"
Mar. Biotechnol. 12, 81-87 (2010)

Shirai, T.; Kuranaga, T.; Wright, J. L. C.; Baden, D. G.; Satake M.; Tachibana K.
"Synthesis of a proposed biosynthetic intermediate of a marine cyclic ether brevisamide for study on biosynthesis of marine ladder-frame polyethers"
Tetrahedron Letters 51, 1394-1396 (2010)

2009年

Kinugawa, M.; Fukuzawa, S.; Tachibana, K.
"Skeletal protein protection: the mode of action of an anti-osteoporotic marine alkaloid, norzoanthamine"
J. Bone Miner. Metab. 27, 303-314 (2009)

Kuranaga, T.; Shirai, T.; Baden, D. G.; Wright, J. L. C.; Satake, M.; Tachibana, K.
"Total Synthesis and Structural Confirmation of Brevisamide, a New Marine Cyclic Ether Alkaloid from the Dinoflagellate Karenia brevis"
Org. Lett. 11, 217-220 (2009)

Konoki, K., Hashimoto, M., Honda, K., Tachibana, K., Hasegawa, F., Tamate, R., Oishi, T., Murata, M.
"Maitotoxin-photoactive probe binds to membrane proteins in blood cells "
Heterocycles 79, 1007-1017 (2009)

Suzuki, H.; Kameyama, A.; Tachibana, K.; Nariitsu, H.; Fukui, K.
"Computationally and Experientally Derived General Rules for Fragmentation of Various Glycosyl Bonds in Sodium Adduct Oligosaccharides"
Anal. Chem. 81, 1108-1120 (2008)

2008年

Sasaki, T.; Kodama, K.; Suzuki, H.; Fukuzawa, S.; Tachibana, K.
"N-terminal Labeling of Proteins by the Pictet-Spengler Reaction"
Bioorg. Med. Chem. Lett. 18, 4550-4553 (2008)

Suzuki, H.; Yamagaki, T.; Tachibana, K.; Fukui, K.
"Fragmentation of Lewis-type Trisaccharides in the Gas Phase: Experimental and Theoretical Studies"
Int. J. Mass Spectrom. 278, 1-9 (2008)

Mimasu, S.; Sengoku, T.; Fukuzawa, S.; Umehara, T.; Yokoyama, S.
"Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25."
Biochem. Biophys. Res. Commun. 366, 15-20 (2008)

Niitsu, A.; Harada, M.; Yamagaki, T.; Tachibana, K.;
"Conformations of 3-carboxylic esters essential for neurotoxicity in veratrum alkaloids are loosely restricted and fluctuate "
Bioorg. med. chem. 16, 3025-3031 (2008)

2007年

Sugiyama, N.; Konoki, K.; Tachibana, K.
"Isolation and Characterization of Okadaic Acid Binding Proteins from the Marine Sponge Halichondria okadai"
Biochemistry 46, 11410-11420 (2007)

Sasaki, M; Tachibana, K.
"Design and synthesis of simplified polycyclic ethers and evaluation of their interaction with an a-helical peptide as a model of target proteins"
Tetrahedron Letters 48, 3181-3186 (2007)

Yamagaki, T.; Suzuki, H.; Tachibana, K.
"Solid-phase Fluorescence and Ionization Efficiency in Negative-ion Matrix-assisted Laser Desorption/Ionization of Neutral Oliogsaccahride: Interaction Between β-Carboline Matrix and Ammonium Salts."
J. Am. Soc. Mass Spectrom 18, 714-723 (2007)

Sasaki, R.; Sasaki, H.; Fukuzawa, S.; Kikuchi, J.; Hirota, H.; Tachibana, K.
"Thermal analyses of phospholipid mixtures by differential scanning calorimetry and effect of doping with a bolaform amphiphile."
Bull. Chem. Soc. Jpn 80, 1208-1216 (2007)

Kodama, K.; Fukuzawa, S.; Nakayama, H.; Kigawa,T.; Sakamoto, K.; Yabuki, T.; Matsuda, N.; Shirouzu, M; Takio, K.; Yokoyama, S.; Tachibana, K.
"Site-specific Functionalization of Proteins by Organopalladium Reactions."
ChemBioChem 8, 232-238 (2007)

2006年

Suzuki, H.; Yamagaki, T.; Tachibana, K.
"Fragmentation of Neutral Oligosacchairdes in Negative-ion MALDI Mass Spectrometry."
Trends in Glycoscience and Glycotechnology 103, 277-292 (2006)

Yamagaki, T.; Suzuki, H.; Tachibana, K.
"Assignments of B-Type Fragments in Postsource Decay of Negative-ion Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry of Neutral Lactooligosaccharides."
J. Mass Spectrom. Soc. Jpn., 54,251-254 (2006)

Kodama, K.; Fukuzawa, S.; Nakayama, H.; Kigawa,T.; Sakamoto, K.; Yabuki, T.; Matsuda, N.; Shirouzu, M; Takio, K.; Tachibana, K.; Yokoyama, S.
"A New Protein Engineering Approach Combining Chemistry and Biology, Part I; Site-specific Incorporation of 4-iodo-L-phenylalanine in vitro Using Mis-acylated Suppressor tRNAPhe."
ChemBioChem 7,1577-1581 (2006)

Fukuzawa, S.; Asanuma, M.; Tachibana, K.; Hirota, H.
"Combination of mixed self-assembled monolayer and matrix-assisted laser desorption/ionization mass spectrometry, a simple tip-based screening method for proteomics."
J. Mass. Spectrom. Soc. Jpn., 53,187-193(2006)

T. Yamagaki, H. Suzuki and K. Tachibana
"Semi-quantative analysis of isomeric oligosaccharides by negative-ion mode UV-MALDI-TOF postsource decay mass spectrometry and their fragmentation mechanism study at N-acetyl hexosamine moiety "
J. Mass Spectrom., 41,454-462 (2006)

T. Yamagaki, K. Fukui and K. Tachibana
"Analysis of glycosyl bond cleavage and related isotope effects in collision-induced dissociation quadrupole-time-of-flight mass spectrometry of isomeric trehaloses "
Anal. Chem., 78,1015-1022 (2006)

T. Yamagaki, H. Suzuki and K. Tachibana
"A comparative study of the fragmentation of neutral lactooligosaccharides in negative-ion mode by UV-MALDI-TOF and UV-MALDI Ion-trap/TOF mass spectrometry "
J. Am. Soc. Mass Spectrom., 17,67-74 (2006)

K. Kodama, S. Fukuzawa, H. Nakayama, T. Kigawa, K. Sakamoto, T. Yabuki, N. Matsuda, M. Shirouzu, K. Takio, K. Tachibana, S. Yokoyama
"Regioselective Carbon-Carbon Bond Formation in Proteins by Palladium-catalysis; New Protein Chemistry via Organometallic Chemistry"
ChemBioChem., 7,134-139 (2006)

2005年

H. Suzuki, T. Yamagaki and K. Tachibana
"Optimization of matrix and amount of ammonium chloride additive for effective ionization of neutral oligosaccharides as chloride ion adducts in negative-mode MALDI-TOF mass spectrometry"
J. Mass Spectrom. Soc. Jpn. 53, 227-229 (2005)

H. Liu, T. Fujiwara, T. Nishikawa, Y. Mishima, H. Nagai, T. Shida, K. Tachibana, H. Kobayashi, Remy E. P., Mangindaan and M. Namikoshi
"Lissoclibadins 1-3, three new polysulfur alkaloids, from the ascidian Lissoclinum cf. badium"
Tetrahedron, 61, 8611-8615 (2005)

S. Fukuzawa, M. Asanuma, K. Tachibana, and H. Hirota
"On-probe sample preparation without washes for matrix-assisted laser desorption/ionization mass spectrometry using an anion exchange medium"
Anal. Chem., 77, 5750-5754 (2005)

T. Shida and K. Tachibana
"Dynamic NMR study on the trans-fused eight-membered ether ring model representing G ring of brevetoxin A"
Tetrahedron Lett., 46, 1855-1858 (2005)

T. Yamagaki, H. Suzuki and K. Tachibana
"In-source and post-source decay in negative-ion matrix assisted laser desorption/ionization time-of-flight mass spectrometry of neutral oligosaccharides"
Anal. Chem., 77, 1701-1707 (2005)

2004年

H. Fuwa, N. Kainuma, K. Tachibana, C. Tsukano, M. Satake, M. Sasaki
"Diverted total synthesis and biological evaluation of gambierol analogues: Elucidation of crucial structural elements for potent toxicity "
Chem. Eur. J. 10, 4894-4909 (2004)

Liu HW, Pratasik SB, T. Nishikawa, T. Shida, K. Tachibana, T. Fujiwara, H. Nagai, H. Kobayashi, M. Namikoshi
"Lissoclibadin 1, a novel trimeric sulfur-bridged dopamine derivative, from the tropical ascidian Lissoclinum cf. badium"
Tetrahedron Lett. 45, 7015-7017 (2004)

H. Fuwa, S. Fujikawa, K.Tachibana, H. Takakura and M. Sasaki
"Convergent Synthesis of the ABCDE Ring Fragment of Ciguatoxins."
Tetrahedron Lett. 45, 4795-4799 (2004)

M. Sasaki, M. Ebine, H. Takagi, H. Takakura, T. Shida, M. Satake, Y. Oshima, T. Igarashi, T. Yasumoto
"Synthesis of the CDE/FG ring models of prymnesins: Reassignment of the relative configuration of the E/F ring juncture"
Org. Lett. 6, 1501-1504 (2004)

2003年

E. Ito, F. Suzuki, K. Toshimori, H. Fuwa, K.Tachibana, M. Satake, M. Sasaki
"Pathological Effects on Mice by Gambierol, Possibly One of the Ciguatera Toxins."
Toxicon, 42, 732-740 (2003)

H. Sasaki, S. Fukuzawa, J. Kikuchi, S. Yokoyama, H. Hirota, and K.Tachibana
"Cholesterol doping induced enhanced stability of bicelles"
Langmuir, 19, 9841-9844 (2003)

H. Sasaki, M. Araki, S. Fukuzawa, and K.Tachibana
"The packing of lipid chains changes the character of bacteriorhodopsin reconstituted in a model membrane."
Bioorg. & Med. Chem. Lett. , 13, 3582-3585 (2003)

M. Izumikawa, M. Murata, K. Tachibana, Y. Ebizuka, and I. Fujii
"Cloning of modular type I polyketide synthase genes from saliomycin producing strain of Streptomyces albus, "
Bioorg. & Med. Chem. Lett. , 11, 3401-3405(2003)

M. Sasaki, C. Tsukano and K. Tachibana.
"Synthetic entry to the ABCD ring fragment of gymnocin-A, a cytotoxic polyether"
Tetrahedron Lett. , 44, 4351-4354(2003)

2002年

H. Fuwa, N. Kainuma, K. Tachibana, M. Sasaki,
"Total Synthesis of (-)-Gambierol,"
J. Am. Chem. Soc., 124, 14983-14992 (2002)

H. Fuwa, M. Sasaki, M. Satake, and K. Tachibana,
"Total Synthesis of Gambierol,"
Org. Lett., 4, 2981-2984 (2002)
[プレス発表](科学技術振興事業団・JST)

H. Takakura, M. Sasaki, S. Honda, and K. Tachibana,
"Progress toward the Total Synthesis of Ciguatoxins: A Convergent Synthesis of the FGHIJKLM Ring Fragment,"
Org. Lett., 4, 2771-2774 (2002)

M. Sasaki, T. Noguchi, and K. Tachibana,
"Intramolecular Radical Cyclization-Ring-Closing Metathesis Approach to Fused Polycyclic Ethers. Convergent Synthesis and Conformational Analysis of the (E)FGH Ring System of Ciguatoxin,"
J. Org. Chem., 67, 3301-3310 (2002)

M. Sasaki, C. Tsukano, and K. Tachibana.
Studies toward the Total Synthesis of Gymnocin A, a Cytotoxic Polyether: A Highly Convergent Entry to the F-N Ring Fragment
Org. Lett., 4, 1747-1750 (2002)

M. Sasaki, M. Ishikawa, H. Fuwa, and K. Tachibana.
A General Strategy for the Convergent Synthesis of Fused Polycyclic Ethers via B-Alkyl Suzuki Coupling. Synthesis of the ABCD Ring Fragment of Ciguatoxin
Tetrahedron, 58, 1889-1911 (2002)

2001年

H. Fuwa, M. Sasaki, and K. Tachibana.
Synthetic Studies toward Gambierol. Convergent Synthesis of the Octacyclic Polyether Core
Org. Lett., 3, 3549-3552 (2001)

M. Sasaki, T. Shida, and K. Tachibana.
Synthesis and Stereochemical Confirmation of the HI/JK Ring System of Prymnesins, Potent Hemolytic and Ichtyotoxic Glycoside Toxins Isolated from the Red Tide Alga
Tetrahedron Lett., 42, 5725-5728 (2001)

R. Sakai, T. Koike, M. Sasaki, K. Shimamoto, C. Oiwa, A. Yano, K. Suzuki, K. Tachibana, and H. Kamiya.
Isolation, Structure Determination and Synthesis of Neodysiherbaine A, a New Excitatory Amino Acid from a Marine Sponge
Org. Lett., 3, 1479-1482 (2001)

H. Fuwa, M. Sasaki, K. Tachibana.
Synthetic Studies on a Marine Polyether Toxin, Gambierol: Stereoselective Synthesis of the EFGH Ring System via B-alkyl Suzuki Coupling.
Tetrahedron, 57,3019 (2001)

H. Takakura, K. Noguchi, M. Sasaki, K. Tachibana.
Synthetic Studies on Ciguatoxin: A Highly Convergent Synthesis of the GHIJKLM Ring System via B-alkyl Suzuki coupling.
Angew. Chem. Int. Ed. Engl., 40,1090 (2001)

2000年

K. Konoki, N. Sugiyama, M. Murata, K. Tachibana, Y, Hatanaka.
Development of Biotin-Avidin Technology to Investigate Okadaic Acid-Promoted Cell Signaling Pathway.
Tetrahedron, 56, 9003 (2000)

M. Izumikawa, M. Murata, K. Tachibana, T. Fujita, H. Naoki.
18O-Labeling Pattern of Okadaic Acid from H218O in Dinoflagellate Prorocentrum Lima Elucidated by Tandem Mass Spectrometry.
Eur. J. Biochem., 267, 5197 (2000)

H. Fuwa, M. Sasaki and K. Tachibana.
Synthetic studies on a marine polyether toxin, gambierol: Stereoselective synthesis of the FGH ring system via B-alkyl Suzuki coupling.
Tetrahedron Lett., 41,8371 (2000)

M. Sasaki, S. Honda, T. Noguchi, H. Takakura and K. Tachibana.
Palladium-Catalyzed Carbonylation of Lactone-Derived Enol Phosphates: Stereoselective Construction of Functionalized Cyclic Ethers from Lactones.
Synlett., 838 (2000)

M. Sasaki, T. Koike, R. Sakai and K. Tachibana.
Total Synthesis of (-)-Dysiherbaine, a Novel Neuroexcitotoxic Amino Acid.
Tetrahedron Lett., 41,3923 (2000)

M. Sasaki, K. Noguchi, H. Fuwa and K. Tachibana.
Convergent synthesis of an HIJK ring model of ciguatoxin via Suzuki cross-coupling reaction.
Tetrahedron Lett., 41,1425 (2000)

S. Paulliac, M. Sasaki, M. Inoue, J. Naar, P. Branaa, M. Chinain, K. Tachibana and A.-M. Legrand.
Characterization of Mice Antisera Elicited with a Ciguatoxin Tetracyclic Synthetic Ring Fragment (JKLM) Conjugated to Carrier Proteins.
Toxicon, 38,669 (2000)

Y. Kobayashi and K. Tachibana.
NMR Observation of Transbilayer Distribution of N-[13C] Methylated Chloropromazine in Asymmetric Lipid Bilayer if Unilamellar Vesicles.
Chem. Lett, 302 (2000)

1999年

M. Inoue, M. Sasaki and K. Tachibana.
A Convergent Synthesis of the Decacyclic Ciguatoxin Model Containing the F-M Ring Framework.
J. Org. Chem., 64, 9416 (1999)

M. Sasaki, M. Inoue, K. Takamatsu and K. Tachibana.
Streocontrolled Synthesis of the JKLM Ring Fragement of Ciguatoxin.
J. Org. Chem., 64, 9399 (1999)

Y. Kobayashi, H. Onuki and K. Tachibana.
Mechanism of Hemolysis and Erythrocyte Transformation Caused by Lipogrammistin-A, a Lipophilic and Acylated Cyclic Polyamine from the Skin Secretion of Soapfishes (Grammistidae).
Bioorg. Med. Chem., 7,2073-2081 (1999)

M. Sasaki, H. Fuwa, M. Ishikawa and K. Tachibana.
A General Method for Convergent Synthesis of Polycyclic Ether based on Suzuki Cross-coupling: Concise Synthesis of the ABCD Ring System of Ciguatoxin.
Org. Lett., 1, 1075-1077 (1999)

N. Matsumori, D. Kaneno, M. Murata, (H. Nakamura) and K. Tachibana.
Stereochemical determination of acyclic structures based on carbon-hydrogen spin-coupling constants. A method of configurational analysis for natural products.
J. Org. Chem., 64, 866-876 (1999)

M. Murata, S. Matsuoka, N. Matsumori, G. K. Paul and K. Tachibana.
Absolute configuration of amphidinol 3, the first complete structure determination from amphidinol homologues: application of a new configuration analysis based on carbon-hydrogen spin-coupling constants.
J. Am. Chem. Soc., 121, 870-871 (1999)

M. Sasaki, T. Noguchi, K. Tachibana.
Synthesis of the FGH ring fragment of ciguatoxin.
Tetrahedron Lett., 40, 1337-1340 (1999)

K. Konoki, N. Sugiyama, M. Murata and K. Tachibana.
Direct Observation of Binding between Biotinylated Okadaic Acids and Protein Phosphatase 2A Monitored by Surface Plasmon Resonance.
Tetrahedron Lett., 40, 887-890 (1999)

1998年

M. Sasaki, H. Fuwa, M. Inoue and K. Tachibana.
New Strategy for Convergent Synthesis of trans-Fused Polyether Frameworks Based on Palladium-Catalyzed Suzuki Cross-Coupling Reaction.
Tetrahedron Lett., 39, 9027-9030 (1998)

M. Murata, M. Izumikawa, K. Tachibana, (T. Fujita) and (H. Naoki).
Labeling pattern of okadaic acid from 18O2 and [18O2]acetate elucidated by collisionally induced dissociation tandem mass spectrometry.
J. Am. Chem. Soc., 120, 147-151 (1998)

M. Inoue, M. Sasaki, K. Tachibana.
Synthetic studies on ciguatoxin: convergent strategy for the construction of the F-M ring framework.
Angew. Chem. Int. Ed. Engl., 37, 965-969 (1998)

H. Onuki, K. Ito, Y. Kobayashi, N. Matsumori and K. Tachibana.
Absolute Structure and Total Synthesis of Lipogramistin-A, a lipophilic Ichthyotoxin of the Soapfish.
J. Org. Chem., 63, 3925-3932 (1998)

I. Tanaka, S. Matsuoka, M. Murata and K. Tachibana.
A New Ceramide with a Novel Branched-Chain Fatty Acid Isolated from the Epiphytic Dinoflagellate Coolia monotis.
J. Nat. Prod., 61, 685-688 (1998)

M. Sasaki, M. Inoue, T. Noguchi, A. Takeichi and K. Tachibana.
Convergent and Stereoselective Method for Synthesis of O-Linked Oxepane Ring System by Intramolecular Radical Cyclization.
Tetrahedron Lett., 39, 2783-2786 (1998)

K. Konoki, M. Hashimoto, M. Murata and K. Tachibana.
Inhibition of Maitotoxin-Induced Ca2+ Influx in Rat Glioma C6 Cells by Brevetoxins and Synthetic Fragments of Maitotoxin.
J. Neurochem., 70, 409-416 (1998)

1997年

Y. Ohnishi and K. Tachibana.
Synthesis of pavoninin-1, a shark repellent defense substance, and its structural analogues toward mechanistic studies on their membrane perturbation.
Bioorg. Biomed. Chem., 5, 2251-2265 (1997)

H. Nakagawa, M. Murata, K. Tachibana and (T. Shiba).
Screening of epiphytic dinoflagellates for dadical scavenging and cytotoxic activities.
Phycol. Res., in press.

(R. Sakai), (H. Kamiya), M. Murata and (K. Shimamoto).
Dysiherbaine: A New neurotoxic amino acid from the Micronesian marine sponge Dysidea herbacea.
J. Am. Chem. Soc., 119, 4112-4116 (1997)

G. K. Paul, N. Matsumori, K. Konoki, M. Murata and K. Tachibana.
Chemical structures of amphidinols 5 and 6 isolated from marine dinoflagellate Amphidinium klebsii and their cholesterol-dependent membrane disruption.
J. Mar. Biotechnol., 5, 124-128 (1997)

(H. Oguri), (S. Hishiyama), (O. Sato), (M. Hirama), M. Murata, (T.Yasumoto) and (N. Harada).
Synthetic study of ciguatoxin. Absolute configuration of C2 hydroxyl group.
Tetrahedron, 53, 3057-3072 (1997)

M. Inoue, M. Sasaki and K. Tachibana.
Construction of fused oxonene ring and reproduction of conformational behavior shown by ring F of ciguatoxin.
Tetrahedron Lett., 38, 1611-1614 (1997)

1996年

T. Nonomura, M. Sasaki, N. Matsumori, M. Murata, K. Tachibana and (T. Yasumoto).
Complete structure of maitotoxin, part II; configuration of the C135-C142 side chain and absolute configuration of the entire molecule.
Angew. Chem., 108, 1786-1789 (1996)
Angew. Chem. Int. Ed. Engl., 35, 1675-1678 (1996)

M. Sasaki, N. Matsumori, T. Maruyama, T. Nonomura, M. Murata, K. Tachibana and (T. Yasumoto).
The complete structure of maitotoxin, part I; configuration of the C1-C14 side chain.
Angew. Chem., 108, 1782-1785 (1996)
Angew. Chem. Int. Ed. Engl., 35, 1672-1675 (1996)

K. Konoki, M. Hashimoto, M. Murata, K. Tachibana and (T. Yasumoto).
Blockade of MTX-induced Ca2+ influx in rat glioma C6 cells by alkylamines.
J. Nat. Toxins., 5, 209-217 (1996)

M. Hu, K. Konoki and K. Tachibana.
Cholesterol-independent membrane disruption caused by triterponoid saponins.
Biochim. Biophys. Acta., 1299, 252-258 (1996)

1991-1995年

G. K. Paul, N. Matsumori, M. Murata and K. Tachibana.
Isolation and chemical structure of amphidinol 2, a potent hemolytic compound from marine dinoflagellate Amphidinium klebsii.
Tetrahedron Lett., 36, 6279-6282 (1995)

(M. Satake), (S. Ishida), (T. Yasumoto), M. Murata, (H. Utsumi) and (T. Hinomoto).
Structural confirmation of maitotoxin on the basis of complete 13C NMR assignments and three-dimensional PFG NOESY-HMQC spectrum.
J. Am. Chem. Soc., 117, 7019-7020 (1995)

N. Matsumori, T. Nonomura, M. Sasaki, M. Murata, K. Tachibana, (M. Satake) and (T.Yasumoto).
Long-range carbon-proton coupling constants for stereochemical assignment of acyclic structure in natural products: Configuration of the C5-C9 portion of maitotoxin.
Tetrahedron Lett., 37, 1269-1272 (1995)

N. Matsumori, M. Murata and K. Tachibana.
Conformational analysis of natural products using long-range carbon-proton coupling constants: Three dimensional structure of okadaic acid in solution.
Tetrahedron, 51, 12229-12238 (1995)

M. Sasaki, N. Matsumori, M. Murata, K. Tachibana and (T. Yasumoto).
Stereochemical assignement of the C35-C39 acyclic likage in maitotoxin: completion of stereochemical determination of C15-C134.
Tetrahedron Lett., 36, 9011-9014 (1995)

T. Nonomura, M. Sasaki, M. Murata and K. Tachibana.
Synthetic approach toward complete structure determination of maitotoxin. Stereochemical assignment of the C63-C68 acyclic linkages.
Tetrahedron Lett., 36, 9007-9010 (1995)

M. Sasaki, T. Nonomura, M. Murata and K. Tachibana.
Synthesis and stereochemical confirmation of the cis-fused L/M and N/O ring systems of maitotoxin.
Tetrahedron Lett., 35, 5023-5026 (1994)

M. Sasaki, M. Inoue and K. Tachibana.
Synthetic studies toward ciguatoxins. Stereocontrolled construction of the KLM ring fragment.
J. Org. Chem., 59, 715-717 (1994)

(K. Sasaki), M. Murata, (T. Yasumoto), (G. .Mieskes) and (A. Takai).
Oxidation of the 27-hydroxy group results in a marked decrease in the affinity of okadaic acid to protein phosphatases.
Biochemical J., 298, 259-262 (1994)

M. Murata, (H. Naoki), (S. Matsunaga), (M. Satake) and (T. Yasumoto)
Structure and partial stereochemical assignments for maitotoxin, the most toxic and largest natural non-biopolymer.
J. Am. Chem. Soc., 116, 7098-7107 (1994)

M. Satake, M. Murata and (T. Yasumoto).
Gambierol, a new toxic polyether compound isolated from the marine dinoflagellate Gambierdiscus toxicus.
J. Am. Chem. Soc., 115, 361-362 (1993)

M. Sasaki, A. Hasegawa and K. Tachibana.
Stereoselective synthesis of a KLM ring model of ciguatoxin: Conformation of the C54 stereochemistry.
Tetrahedron Lett., 34, 8489-8492 (1993)

H. Onuki, K. Tachibana, (N. Fusetani).
Structure of lipogrammistin-A, a lipophilic ichthyotoxin secreted by the soapfish Diploprion bifascatum.
Tetrahedron Lett., 34, 5609-5612 (1993)

(H. Naoki), M. Murata and (T. Yasumoto).
Nagetive FAB tandem mass spectrometry for structural study on polyether compounds; structural verification of yessotoxin.
Rapid Commun. Mass Spectrom., 7, 179-182 (1993)

M. Murata, (H. Naoki), (T. Iwashita), (M. Sasaki), (A. Yokoyama) and (T. Yasumoto).
Structure of maitotoxin.
J. Am. Chem. Soc., 115, 2060-2062 (1993)

(C. J. Barrow), (K. Nakanishi), and K. Tachibana.
Structure and activity studies of pardaxin and analogues using model membranes of phosphatidylcholine.
Biochim. Biophys. Acta., 1112, 235-240 (1992)

(M. G. Zagorski), (D. G. Norman), (C. J. Barrow), (T. Iwashita), K. Tachibana, and (D. J. Patel).
Solution structure of pardaxin P-2.
Biochemistry, 30, 8009-8017 (1992)

M. Sasaki, K. Tachibana, and (H. Nakanishi).
An efficient and stereocontrolled synthesis of the nephritogenoside core structure.
Tetrahedron Lett., 32, 6873-6876 (1991)

conference

S. Paulliac, M. Sasaki, J. Naar, M. Inoue, P. Branaa, P. Cruchet, M. Chinain and A.-M. Legrand.
IImmunochemical Methods for Ciguatoxins Detection in Pacific Herbivorous and Carnivorous Fish.
Proceeding of the 5th Indo-Pacific Conference, eds. B. Seret and J.-Y. Sire (Society of French Ichthyology), pp. 759-773.

K. Ohtsuki, T. Shida, T. Yamagaki, M. Murata, K. Tachibana and A. Mahakhant.
Isolation and Chemical Characterization of Allelopathic Factors Between Cyanobateria.
Proceedings of International Conference on Asian Network on Microbial Research, Chiang Mai, Thailand, Thailand Institute of Scientific and Technological Research, The Institute of Physical and Chemical Research (RIKEN), and Science and Thechnology Agency, Japan, suppl., 8 pp. (1999).

H. Nakanishi and T. Yamagaki.
Post-Source Decay (PSD) Fragment Analysis of MALDI-TOF Mass Spectrometry of Carbohydrates. I: Structural Isomer Analyses.
Glycoconjugate J., 16, s111(1999).

S. Paulliac, M. Inoue, M. Sasaki, J. Naar, M. Murata, K. Tachibana, M. Chinain and A.-M. Legrand.
Production of monoclonal antibodies to CTX using a tetracyclic synthetic fragment (JKLM) conjugated to carrier proteins and cross-reactivity studies towards related polyether compound.
Proceedings of the VIII International Conference of Harmful Algae (Vigo, Spain).

G. K. Paul, N. Matsumori, K. Konoki, M. Sasaki, M. Murata and K. Tachibana.
Structure of amphidinol 3 and its cholesterol-dependent membrane perturbation: a strong antifungal metabolite produced by dinoflagellate, Amphidinium kiebsii.
Harmful and Toxic Algal Blooms, eds. T. Yasumoto, Y. Oshima and Y. Fukuyo (Intergovernmental Oceanographic Commission of UNESCO, Paris), pp. 503-506 (1996).

(T. Igarashi), (Y. Oshima), M. Murata and (T. Yasumoto).
Chemical studies on prymnesins isolated from Prymnesium parvum.
Harmful Marine Algal Blooms, eds. P. Lassus (Lavoisler, Intercept Ltd., Paris), pp. 303-308 (1996).

M. Sasaki, M. Inoue, M. Murata and K. Tachibana.
Synthesis of a tetracyclic fragment of ciguatoxin toward preparation of an artificial antigen for ciguatoxin immunoassay.
Proceedings of International Symposium on Ciguatera and Marine Natural Products, eds. Y. Hokama, P. J. Scheuer and T. Yasumoto (Asian-Pacific Research Foundation, Honolulu), pp. 229-237 (1995).

K. Konoki, M. Sasaki and K. Tachibana.
Membrane perturbation of pardaxins, defensive peptides of flatfish.
Peptide Chemistry 1992, eds. N. Yanaihara (ESCOM Science Pub., Leiden), pp. 402-405 (1993).

著書

児玉 公一郎, 中山 洋, 福沢 世傑.
炭素―炭素結合をタンパク質に導入する―遺伝子工学と有機合成化学の融合
化学と生物, 46, 528-530 (2008).

橘 和夫、巻頭言
合成標的化合物の選択. 有機合成
化学協会誌 65, 800 (2007).

福沢世傑
紐形、扇形、環形、外肛、および半索動物、海洋生物成分の利用「マリンバイオのフロンティア」
pp 132-144、伏谷伸宏監修、シーエムシー、東京、2005年3月31日

橘 和夫
私が化学者になった理由:自然の不思議を解明する化学にであう.化学 60(5), 24 (2005).

橘 和夫.
生体機能解明のための試薬としての海産毒
先端化学シリーズX:海洋天然物、錯体、コンビナトリアル、全合成, 76-82 (2003).

佐々木 誠、井上将行.
ポリエーテル系天然物の化学合成―新しい中員環エーテルの構築法とエーテル環連結法の開発
有機合成化学協会誌, 59, 193-205 (2001).

橘 和夫.
海洋天然物化学-現状と未来
生物工学会誌, 77, 147-164 (1999).

佐々木 誠.
質量分析法による構造解析-マススペクトルで有機分子の構造を見る.
化学と教育, 46(11), 730-734 (1998).

橘 和夫.
生理活性物質と海洋.
化学と工業, 48, (1997).

村田道雄, 松森信明, 橘 和夫.
炭素−水素間の遠隔スピン結合を利用した2次元NMRによる鎖状有機化合物の立体配置解析.
日本化学会誌, (1997).

佐々木 誠, 村田 道雄.
マイトトキ・Vンの完全構造決定.
有機合成化学協会誌, 55, 535-546 (1997).

橘 和夫.
見聞を広げよう―他分野の有益な情報のつかみ方.
化学, 52, 26-27 (1997).

佐々木 誠.
マイトトキシンの完全構造が決まった―非ポリマ−系の天然物としては最大, 試薬としての役割に期待.
化学と生物, 34, 635-637 (1996).

佐々木 誠.
赤潮毒ブレベトキシンBが全合成された.
化学と生物, 34, 605-606 (1996).

村田道雄.
渦鞭毛藻とアレロケミックス.
化学と工業, 49, 1029-1031 (1996).

村田道雄.
微細藻の毒.
化学と生物, 34, 311-320 (1996).

佐々木 誠.
超活性海産毒マイトトキシンの立体構造解析−有機合成とNMRによるアプロ−チ.
化学と工業, 49, 151-154 (1996).

橘 和夫.
第一線研究室を訪ねる:化学を武器に生命現象の解明に挑む.
化学, 50, 742-745 (1995).

村田道雄.
パリトキシンの起源は渦鞭毛藻.
化学, 50, 698 (1995).

村田道雄, 橘 和夫.
渦鞭毛藻の生き残り戦略.
バイオサイエンスとインダストリー, 53, 883-885 (1995).

(K. L. Rinehart) and K. Tachibana.
The 1994 Japan-U.S.seminar on bioorganic marine chemistry, meeting report.
J. Nat. Prod., 58, 344-358 (1995).

佐々木 誠.
抗腫瘍性ポリエーテルマクロリドハリコンドリンBの全合成.
化学, 48, 74-75 (1993).

橘 和夫.
サメのきらいな化学物質.
化学増刊 121: 「化学で探る海洋生物の謎」, 安元 健(編), 化学同人, pp. 63-70 (1992).

橘 和夫.
化学ばなれのすすめ.
化学と工業, 45, 753-755 (1992).

橘 和夫.
魚類防御因子の忌避作用と捕食魚の生体膜―魚毒性ペプチドに膜の透過性に影響を及ぼす化学構造.
化学と生物, 29, 622-624 (1991).

橘 和夫.
生物がつくる毒と薬.
東京大学公開講座 62:「くすり」, 吉川弘之らと共著, 東京大学出版・・ p.49-74 (1996).

村田道雄.
第7章 微量天然物の構造解析,
天然物有機化合物の構造解析, 伏谷伸宏, 広田洋(編), シュプリンガー・フェアラーク東京, p. 293-317 (1994).

T. Murae and M. Sasaki.
Synthetic approaches toward antitumor fquassinoids.
Studies in natural products chemistry, Vol. 11: Stereoselective synthesis, eds. Atta-ur-Rahman (Elsevier), pp. 72 (1992).

橘 和夫.
分取クロマトグラフィーの実際―天然物を中心に.
小村 啓と共著, 東京化学同人(1990). 
原著: K. Hostettmann, M. Hostettman and A. Marston. Preparative chromatography techniques: Applications in natural product isolation. Springer-Verlag (Berlin, Heiderberg) (1986).

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