尹 貽貞Yizhen Yin

博士研究員

日本学術振興会 特別研究員(PD)


City/county of origin
Taian City, Shandong Province, People's Republic of China
Hobbies
Travelling, Pingpong, Soccer, Reading, Painting and Calligraphy, Chess…
Places You Like
Any places having rivers and mountains
Where for a big vacation
Qingdao, Hokkaido, Okinawa, Hawaii and Europe
What are your strong points?
My previous members tell me that my champion point is my smiling. (kidding)
Music: what is some intense music for intense lab work?
The Little Tigers
What are people in the lab doing?
Improving themselves and becoming more and more professional
What was surprising about the suga lab
Such a big group and free study environment
Original motivation towards science?
Dream and curiosity
A few words for future lab mates
Let’s be good friends.
Science is ……
Science is an art for searching the truth and creating a more beautiful world.

学歴・職歴

2008.06:
Bachelor degree in Pharmacy, Anhui Medical University.
2011.06:
Master degree in Medicinal Chemistry, Shandong University.
2011.10:
Research Student in Bioorganic and Synthetic Chemistry, Kyushu University.
2015.03:
PhD in Bioorganic and Synthetic Chemistry, Kyushu University.
2015.04:
Postdoctoral fellow in Bioorganic Chemistry, The University of Tokyo.


発表論文

"Effects of 8-halo-7-deaza-2'-deoxyguanosine triphosphate on DNA synthesis by DNA polymerases and cell proliferation."
Y. Yin; S. Sasaki; Y. Taniguchi
Bioorg Med Chem, 24, 3856-3861 (2016)
"Inhibitory Effect of 8-Halogenated 7-Deaza-2'-deoxyguanosine Triphosphates on Human 8-Oxo-2'-deoxyguanosine Triphosphatase, hMTH1, Activities."
Y. Yin; S. Sasaki; Y. Taniguchi
Chembiochem, 17, 566-569 (2016)
"Recognition and excision properties of 8-halogenated-7-deaza-2'-deoxyguanosine as 8-oxo-2'-deoxyguanosine analogues and Fpg and hOGG1 inhibitors."
Y. Yin; S. Sasaki; Y. Taniguchi
Chembiochem, 16, 1190-1198 (2015)
"Synthesis of 8-halogenated-7-deaza-2 '-deoxyguanosine as an 8-oxo-2 '-deoxyguanosine analogue and evaluation of its base pairing properties."
Y.Z. Yin; Y. Taniguchi; S. Sasaki
Tetrahedron, 70, 2040-2047 (2014)
"Recoverable Pd/C catalyst mediated dehydrogenation of sterols and an improved synthesis of 1 alpha-hydroxydehydroepiandrosterone."
Y.Z. Yin; C. Liu; L.Q. Tang; Z.P. Liu
Steroids, 77, 1419-1422 (2012)
"Advances in the Synthesis of A-Ring 1,7-Enyne Synthons for Active Vitamin D-3 Analogues."
Y.Z. Yin; J.P. Li; C. Liu; L.Q. Tang; Z.P. Liu
Current Organic Synthesis, 8, 374-392 (2011)
"Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands."
B.L. Gao; C.M. Zhang; Y.Z. Yin; L.Q. Tang; Z.P. Liu
Bioorganic & Medicinal Chemistry Letters, 21, 3730-3733 (2011)
"Tumor-related signalling pathways targeted by the active Vitamin D3 (in Chinese)."
Y.Z. Yin; Z.P. Liu
Chemistry of Life, 29, 552-556 (2009)

連絡先

    • E-mail… yizhenyin@(@以下はchem.s.u-tokyo.ac.jp)