Naohiro Terasaka, Ph.D.

Project Assistant Professor

ORCID

Education

2010:

B.Sc., School of Engineering, The University of Tokyo
Thesis advisor Prof. Tsutomu Suzuki

2012:

M.Sc., Graduate School of Engineering, The University of Tokyo
Thesis advisor Prof. Hiroaki Suga

2015:

Ph.D., Graduate School of Science, The University of Tokyo
Thesis advisor: Prof. Hiroaki Suga

Professional career

2012-2015

Research Fellow of the Japan Society for the Promotion of Science

2015-2018

Postdoctoral research associate, ETH Zurich
(HFSP Long-term fellowship)
Advisor, Prof. Donald Hilvert

2018-present

Project assistant professor, Graduate School of Science, The University of Tokyo

Publication

"An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch."

S. Ishida; N. Terasaka; T. Katoh; H. Suga

Nat Chem Biol, (2020)

"Cytoplasmic glycoengineering enables biosynthesis of nanoscale glycoprotein assemblies."

H.L.P. Tytgat; C.L. Lin; M.D. Levasseur; M.B. Tomek; C. Rutschmann; J. Mock; N. Liebscher; N. Terasaka; Y. Azuma; M. Wetter; M.F. Bachmann; D. Hilvert; M. Aebi; T.G. Keys

Nat Commun, 10, 5403 (2019)

"Generation of non-standard macrocyclic peptides specifically binding TSC-22 homologous gene-1."

S.T.P. Tran; C.J. Hipolito; H. Suzuki; R. Xie; H.D.K. Tuyen; P. ten Dijke; N. Terasaka; Y. Goto; H. Suga; M. Kato

Biochem Bioph Res Co, 516, 445-450 (2019)

"Laboratory evolution of virus-like nucleocapsids from nonviral protein cages."

N. Terasaka; Y. Azuma; D. Hilvert

Proc. Natl. Acad. Sci. U. S. A., (2018)

"Modular protein cages for size-selective RNA packaging in vivo."

Y. Azuma; T. Edwardson; N. Terasaka; D. Hilvert

J. Am. Chem. Soc., 140, 566-569 (2018)

"A human microRNA precursor binding to folic acid discovered by small RNA transcriptomic SELEX."

N. Terasaka; K. Futai; T. Katoh; H. Suga

RNA, 22, 1918-1928 (2016)

"tRid, an enabling method to isolate previously inaccessible small RNA fractions."

K. Futai; N. Terasaka; T. Katoh; H. Suga

Methods, 106, 105-111 (2016)

"Recent Developments of Engineered Translational Machineries for the Incorporation of Non-Canonical Amino Acids into Polypeptides."

N. Terasaka; Y. Iwane; A.S. Geiermann; Y. Goto; H. Suga

Int J Mol Sci, 16, 6513-6531 (2015)

"An orthogonal ribosome-tRNA pair via engineering of the peptidyl transferase center."

N. Terasaka; G. Hayashi; T. Katoh; H. Suga

Nat. Chem. Biol., 10, 555-557 (2014)

"Flexizymes-facilitated genetic code reprogramming leading to the discovery of drug-like peptides."

N. Terasaka; H. Suga

Chem. Lett., 43, 11-19 (2014)

"The RNA origin of transfer RNA aminoacylation and beyond."

H. Suga; G. Hayashi; N. Terasaka

Phil. Trans. R. Soc. B, 366, 2959-2964 (2011)

"Crystallization and preliminary X-ray diffraction analysis of an archaeal tRNA-modification enzyme, TiaS, complexed with tRNA(Ile2) and ATP."

T. Osawa; H. Inanaga; S. Kimura; N. Terasaka; T. Suzuki; T. Numata

Acta crystallographica. Section F, Structural biology and crystallization communications, 67, 1414-1416 (2011)

"Structural basis of tRNA agmatinylation essential for AUA codon decoding."

T. Osawa; S. Kimura; N. Terasaka; H. Inanaga; T. Suzuki; T. Numata

Nat. Struct. Mol. Biol., 18, 1275-1280 (2011)

"Biogenesis of 2-agmatinylcytidine catalyzed by the dual protein and RNA kinase TiaS."

N. Terasaka; S. Kimura; T. Osawa; T. Numata; T. Suzuki

Nat. Struct. Mol. Biol., 18, 1268-1274 (2011)

Contact Info

• Room #2208, West wing, Chemistry Bildg.
  Department of Chemistry, Graduate School of Science, The University of Tokyo
• E-mail… n_terasaka"at"chem.s.u-tokyo.ac.jp (change "at" to @)
• TEL…+81-3-5841-4638
• FAX…+81-3-5841-8372