concept image

Philosophy of Suga lab.

In the Suga lab, our aim is to utilize organic chemistry techniques in combination with biology to tackle yet unresolved questions. In our inclusive research, we procure scientific knowledge leading to new concepts and develop novel technologies with broad applicability, which can extend to drug discovery. We provide a diligent and cooperative research environment with a goal of nurturing individuals so they are brimming with innovation and global-mindedness.

Lab News

Oct, 2023:
Mr. Miura (D3) won the travel award at the 13th International Peptide Symposium. Congrats!
Aug, 2023:
Mr. Uchida (M2) and Mr. Hirashima (B4) won the Best Discussion Award at the 55th Peptide Summer School. Congrats!
Mr. Eu Tchen Ang (D2) won the Best Failed Award at the 55th Peptide Summer School. Congrats!
Ms. Aizawa, Mr. Imai, Mr. Saito, Mr. Nishio (M2) and Ms. Yanagi and Mr. Nakagawa (M1) and Mr. Hirashima (B4) won the Excellent Poster Presentation Award at the 55th Peptide Summer School. Congrats!
Mr. Maxwell Sigal (D1) won the Excellent Presentation Awardand at the 55th Peptide Summer School. Congrats!
M1 and M2 students won the Laboratory Introduction Award at the 55th Peptide Summer School. Congrats!
May, 2023:
Ms. JunShi Chang(D2) won the oral presentation award at the 103rd CSJ annual meeting. Congrats!
May, 2023:
Ms. JunShi Chang(D2) won the oral presentation award at the 103rd CSJ annual meeting. Congrats!
Ms. JunShi Chang(D2) won the oral presentation award at the 143rd PSJ annual meeting. Congrats!
Ms. Huang (D2) won the student travel award at the Boulder Peptide Symposium 2023. Congrats!
Apr, 2023:
Ms. Lu won the Award of Excellence in the final examination of IGPEES fellowship. Congrats!
Ms. Matsumoto won Designing Future Society Fellowship. Congrats!
Mr. Kashiwa won Fellowship for Integrated Materials Science and Career Development. Congrats!
Seven members joined the lab.
Mar, 2023:
Ms. Yanagi won the scholar of excellence award from Faculty of Science. Congrats!
Six members graduated from the lab.
Feb, 2023:
Prof. Suga will be awarded the 2023 Wolf Prize in Chemistry. Congrats!→link
Dec, 2022:
Mr. Ohno (D1) won the Excellent Poster Award at the 12th CSJ Chemistry Festa 2022. Congrats!
Nov, 2022:
Mr. Miura (D2) won the student travel award at the Boulder Peptide Symposium 2022. Congrats!
Oct, 2022:
Mr. Imai and Mr. Nishio won MERIT-WINGS fellowship. Congrats!
Aug, 2022:
The Suga lab students won the best laboratory introduction award in the 54th Peptide Summer School. Also, Mr. Kashiwa (D1) and Mr. Uchida (M1) won the Excellent Poster Presentation Award. Congrats!
June, 2022:
Dr. Terasaka has been promoted to an associate professor at ELSI, Tokyo Institute of Technology. Congratulations!
Mr. Miura(D2) won the best poster presentation award at the 21st University of Tokyo Life Science Symposium. Congrats!
May, 2022:
Ms. Takahashi(D1) and Mr. Renier van Neer (D3) won the oral presentation award at the 102nd CSJ annual meeting. Congrats!
One member joined the lab.
Apr, 2022:
Five members joined the lab.
Ms. Huang, Mr. Kanayama and Mr. Miura won JSPS fellowship. Congrats!
Mar, 2022:
Six members graduated from the lab.
Dr. Liu, Mr Ohno and Mr. Uchida won the scholar of excellence award from Graduate school of Science and Department of Chemistry.→link
Feb, 2022:
Dr. Tajima's paper regarding Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P has been published in Nucleic Acids Research!→link
Dr. Nagano's paper regarding Inner residues of macrothiolactone in autoinducer peptides I/IV circumvent spontaneous S-to-O acyl transfer to the upstream serine residue has been published in RSC Chemical Biology!→link
Dr. Nagano's paper regarding Chemical peptide macrolactonization via intramolecular S-to-S-to-O acyl transfer has been published in Peptide Science!→link
Jan, 2022:
Assoc. Prof. Katoh's paper regarding In Vitro Selection of Foldamer-Like Macrocyclic Peptides Containing 2-Aminobenzoic Acid and 3-Aminothiophene-2-Carboxylic Acid has been published in J Am Chem Soc!→link
Dec, 2021:
The paper regarding Potent macrocycle inhibitors of the human SAGA deubiquitinating module has been published in Cell Chem Biol!→link
Dr. Zhang's paper regarding LimF is a versatile prenyltransferase catalyzing histidine-C-geranylation on diverse nonnatural substrates has been posted in ChemRxiv!→link
Nov, 2021:
The paper regarding Macrocyclic Peptide-Conjugated Tip for Fast and Selective Molecular Recognition Imaging by High-Speed Atomic Force Microscopy has been published in ACS Appl Mater Interfaces!→link
Mr. Taguchi and Mr. Shinbara won SPRING GX fellowship. Congrats!
Assoc. Prof. Katoh's paper regarding Consecutive Ribosomal Incorporation of α-Aminoxy/α-Hydrazino Acids with L/D-Configurations into Nascent Peptide Chains has been published in J Am Chem Soc!→link
Ms. Liu's paper regarding An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold has been published in J Am Chem Soc!→link
The paper regarding Discovery and Development of Cyclic Peptide Inhibitors of CIB1 has been published in ACS Med Chem Lett!→link
Oct, 2021:
Dr. Yuchen Zhang won the Excellent Stone Award from the 58th Japanese Peptide Society. Congrats!
Ms. Wenyu Liu won the Good Stone Award from the 58th Japanese Peptide Society. Congrats!
Mr. Kawakami and Shinbara won the Excellent Poster Award from the 58th Japanese Peptide Society. Congrats!
Dr. Komatsu and Assis. Prof. Teraska's paper regarding De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist in iScience!→link
Mr. Kashiwa won MERIT-WINGS fellowship. Congrats!
Six members joined the lab.
Sep, 2021:
The paper regarding De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition has been published in eLife!→link
The paper regarding Site-Specific Nonenzymatic Peptide S/O-Glutamylation Reveals the Extent of Substrate Promiscuity in Glutamate Elimination Domains has been published in J Am Chem Soc!→link
Aug, 2021:
Mr. Yuto Ohno, Ms. Rei Takahashi and Ms. Chang Jun Shi won the Excellent Poste Presentation Award in the 53rd Peptide Summer School.
Congratulations!→link
Jun, 2021:
Two members joined the lab.
May, 2021:
One member joined the lab.
The paper regarding Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming has been published in J Med Chem!→link
 
Dr. Iwane and Mr. Kimura's paper regarding Uniform affinity-tuning of N-methyl-aminoacyl-tRNAs to EF-Tu enhances their multiple incorporation has been published in Nucleic Acids Reserach!This was selected as NAR Breakthrough Article→link
The paper regarding Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models has been published in Nat Commun!→link
   
Apr, 2021:
   
Ms. Liu (D3) won the oral presentation award at the 101st CSJ annual meeting. Congrats!
   
Mr. Murakami won WINGS-CFS fellowship. Congrats!
 
We updated the publication list.
Ms. Imanishi's paper regarding In Vitro Selection of Macrocyclic d/l-Hybrid Peptides against Human EGFR in J Am Chem Soc!→link
Severn members joined the lab.
Mr. Kawakami and Ms. Kawai won JSPS fellowship. Congrats!
   
Mr. Miura won Designing Future Society Fellowship. Congrats!
Mr. Zhao won Fellowship for Integrated Materials Science and Career Development. Congrats!
Mr. Kanayama won IGPEES presentation award. Congrats!
Mar, 2021:
Three members graduated from the lab.
Mar, 2021:
 
Dr. Nagano's paper regarding One-Pot In Vitro Ribosomal Synthesis of Macrocyclic Depsipeptides has been published in J. Am. Chem. Soc.!→link
Mr. Zhao won the scholar of excellence award from Graduate school of Science and Department of Chemistry.→link
The paper regarding Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins has been published in Nat Commun!→link
Feb, 2021:
Mr Tsutsumi and Dr. Kuroda's paper regarding Posttranslational chemical installation of azoles into translated peptides has been published in Nat Commun!→link
Dec, 2020:
Dr. Rogers's paper regarding In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides has been published in RSC Chem Biol!→link
One member joined the lab.
Nov, 2020:
Mr. Ohno won MERIT-WINGS fellowship. Congrats!
Dr. Bashiruddin's paper regarding Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation in Proc Natl Acad Sci USA!→link
Assis. Prof. Vinogradov's paper regarding Accurate Broadcasting of Substrate Fitness for Lactazole Biosynthetic Pathway from Reactivity-Profiling mRNA Display has been published in J Am Chem Soc!→link
Two members joined the lab.
Ms. Takahashi won WINGS-CFS fellowship. Congrats!
Oct, 2020:
The paper regarding Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins has been posted in Research Square!→link
Dr Walport's paper regarding Cyclic peptides can engage a single binding pocket through highly divergent modes has been published in Proc Natl Acad Sci USA!→link
Dr. Wiedmann's paper regarding Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the Staphylococcus aureus receptor histidine kinase, AgrC has been published in Chemical Communications!→link
Two members joined the lab.
Sep, 2020:
Assoc. Prof. Katoh's paper regarding Ribosomal Elongation of Aminobenzoic Acid Derivatives has been published in J Am Chem Soc!→link
Dr. Gao's paper regarding GTP-State-Selective Cyclic Peptide Ligands of K-Ras(G12D) Block Its Interaction with Raf has been published in ACS Central Science!→link
   
Sep, 2020:
One member graduated from the lab.
Aug, 2020:
Assoc. Prof. Katoh's paper regarding Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids has been published in Nat Chem!→link
Aug, 2020:
Assis. Prof. Vinogradov's paper regarding Promiscuous Enzymes Cooperate at the Substrate Level En Route to Lactazole A has been published in J Am Chem Soc!→link
July, 2020:
Ms. Okuma's paper regarding A macrocyclic peptide library with a structurally constrained cyclopropane‐containing building block leads to thiol‐independent inhibitors of phosphoglycerate mutase has been published in Chem Asian J!→link
Dr. Yin's paper regarding Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy has been published in Cell Chem Biol!→link
May, 2020:
Assis. Prof. Vinogradov's paper regarding Minimal lactazole scaffold for in vitro thiopeptide bioengineering has been published in Nat Commun!→link
Apr, 2020:
Mr. Neer won Mitsubishi Corporation International Scholarship. Congrats!
Dr. Passioura's paper regarding Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display has been published in J Am Chem Soc!→link
Apr, 2020:
Five member joined the lab.
Mr. Miura won WINGS-CFS fellowship. Congrats!
Mr. Komatsu and Ms. Liu won JSPS fellowship. Congrats!
Mr. Kanayama won IGPEES presentation award. Congrats!
We updated the publication list.
Mar, 2020:
Five members graduated from the lab.
Mar, 2020:
Dr. Otero's paper regarding Macrocyclic peptides that inhibit Wnt signalling via interaction with Wnt3a in RSC Chem Biol!→link  
We updated the publication list.
Mar, 2020:
Dr. Ishida and Assis. Prof. Terasaka's paper regarding An aminoacylation ribozyme evolved from a natural tRNA-sensing T-box riboswitch in Nat Chem Biol!→link
Dr. Ishida and Mr. Ohno won the scholar of excellence award from Graduate school of Science and Department of Chemistry, respectively.→link
Mar, 2020:
Assoc. Prof. Katoh's paper regarding Ribosomal Elongation of Cyclic γ-Amino Acids using a Reprogrammed Genetic Code in J Am Chem Soc!→link
Feb, 2020:
Dr. Huang's paper regarding Affinity Maturation of Macrocyclic Peptide Modulators of Lys48-linked Diubiquitin by a Twofold Strategy has been published in Chem Eur J!→link
We updated the publication list.
Dec, 2019:
Professor Suga won the Bohlmann Lecture 2019! Congrats!!→link
Professor Suga won du Vigneaud Award 2019! Congrats!!→link
   
Dr. Tsiamantas's paper regarding Ribosomal incorporation of aromatic oligoamides as peptide side‐chain appendages in Angewandte Chemie!→link
We updated the publication list.
Nov, 2019:
Professor Suga won the WIRED Audi INNOVATION AWARD 2019! Congrats!!→link
   
Dr. Maini and Mr Kimura's paper regarding Ribosomal Formation of Thioamide Bond in Polypeptide Synthesis has been published in J Am Chem Soc!→link
Nov, 2019:
Dr. Yin's paper regarding De novo carborane-containing macrocyclic peptides targeting human EGFR has been published in J Am Chem Soc!→link
Dr Walport's paper regarding Cyclic peptides can engage a single binding pocket through multiple, entirely divergent modes has been submitted to bioRxiv!→link
Assis. Prof.Vinogradov's paper regarding Minimal lactazole scaffold for in vitro production of pseudo-natural thiopeptides has been submitted to bioRxiv!→link
Oct, 2019:
Mr. Yamato Komatsu was awarded the Best Poster Award at the 56th Japanese Peptide Symposium.
Congratulations!→link
Dr. Kato's paper regarding Chemoenzymatic posttranslational modification reactions for the synthesis of Ψ [CH2NH]‐containing peptides has been published in Angewandte Chemie!→link
Associate Professor Goto's paper regarding In vitro biosynthesis of peptides containing exotic azoline analogs has been published in ChemBioChem!→link
Sep, 2019:
Four members joined the lab.
Aug, 2019:
Ms. Marina Kawai was awarded the Excellent Presentation Award in the 51st Peptide Summer School.
Congratulations!→link
Mr. Koki Shinbara was awarded the Excellent Poster Award in the 51st Peptide Summer School.
Congratulations!→link
M1 students were awarded the Laboratory Introduction Award in the 51st Peptide Summer School.
Congratulations!→link
July, 2019:
Mr. Satoshi Ishida was awarded the Best Presentation Award at the 21st Annual Meeting of the RNA Society of Japan.
Congratulations!→link
June, 2019:
Mr. Gun Ikarashi was awarded the Excellent Poster Award at the 43rd Symposium on Organic Electron Transfer Chemistry.
Congratulations!→link
Assis. Prof. Terasaka was awarded Young Scientist Award at the Joint Annual Meeting of 71st JSCB & 19th PSSJ.
Congratulations!→link
We updated the publication list.
May, 2019:
Dr. Rogers's paper regarding De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains has been published in Nat Chem!→link
Dr. Hirose and Mr. Hideshima's paper regarding A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display has been published in ChemBioChem!→link
Dr. Tsiamantas's paper regarding Optimizing Aromatic Oligoamide Foldamer Side-Chains for Ribosomal Translation Initiation has been published in Chem Commun!→link
We also updated the publication list.
May, 2019:
One member graduated from the lab.
Dr. Passioura and Dr. Ito's paper regarding Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor has been published in Nature Chemical Biology!→link
We also updated the publication list.
Apr, 2019:
Eight member joined the lab.
Mar, 2019:
Eight members graduated from the lab.
Assoc. Prof. Katoh's paper regarding Flexizyme-catalyzed synthesis of 3′-aminoacyl-NH-tRNAs in Nucleic Acids Res.!→link
Dr. Yin's paper regarding Chemical and Ribosomal Synthesis of Topologically Controlled Bicyclic and Tricyclic Peptide Scaffolds Primed by Selenoether Formation in Angew. Chem. Int. Ed.!→link
Feb, 2019:
One member graduated from the lab.
Jan, 2019:
Dr. Takatsuji's paper regarding Ribosomal synthesis of backbone-cyclic peptides compatible with in vitro display has been published in J. Am. Chem. Soc.!→link
Jan, 2019:
We updated the publication list.
Dec, 2018:
Three members graduated from the lab.
At 10th International Peptide Symposium, Mr. Otero and Dr. Huang won the excellent poster presentation award. Congrats!→link
We also updated the publication list.
Nov, 2018:
4th International Conference on Circular Proteins and Peptides, Mr. Miyairi and Mr. Kawakami won the excellent poster presentation award. Congrats!→link
Oct, 2018:
Dr Rogers and Dr. Passioura's paper regarding Nonproteinogenic deep mutational scanning of linear and cyclic peptides has been published in Proceedings of the National Academy of Sciences!→link
We also updated the publication list.
Oct, 2018:
Two new members joined the lab!
Sep, 2018:
Dr. Passioura's paper regarding de novo macrocyclic peptide inhibitors of Hepatitis B Virus cellular entry has been published in Cell chemical biology!→link
Dr. Passioura's paper regarding Display Selection of Exotic Macrocyclic Peptides Expressed under a Radically Reprogrammed 23 Amino Acid Genetic Code has been published in J. Am. Chem. Soc.!→link
Dr. Katoh's paper regarding Ribosomal Incorporation of Consecutive beta-Amino Acids has been published in J. Am. Chem. Soc.!→link
We also updated the publication list.
Sep, 2018:
Two new members joined the lab!
 
Aug, 2018:
At the 50th Peptide Summer School, Mr. Kawakami won the best presentation award. Congrats!→link
    
Jun, 2018:
Assistant Professor Terasaka joined the lab!
May, 2018:
One new member joined the lab!
Apr, 2018:
Seven new members joined the lab!
Mar, 2018:
Dr. Rogers' paper regarding ribosomal synthesis of peptide-foldamer hybrids has been published in Nature Chemistry!→link We also added several other papers into the publication list.
Dec, 2017:
Professor Suga won the Nagoya Silver Medal! Congrats!!→link
Nov, 2017:
Assistant Professor Katoh's paper regarding engineering of D-arm and T-stem of tRNA has been published in Nucleic Acids Res.!→link We also added seven other papers into the publication list.
Nov, 2017:
Associate Professor Goto won the 1st Bioindustry Research Award. Congrats!
Aug, 2017:
At the 49th Peptide Summer School, We won the laboratory introduction award! Mr. Komatsu and Mr. Miyairi won the best discussion award and the poster presentation award, respectively. Congrats!
Jun, 2017:
Dr. Song's paper regarding inhibitors of the protein-protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 5 has been published in Org. Biomol. Chem.!→link
Jun, 2017:
Drs. Obexer and Walport won the grand prix award and TOP 5 presentation award, respectively, in the Young Investigator Poster Competition at 9th International Peptide Symposium (Whistler, Canada). Congrats!
Apr, 2017:
Dr. Kato (graduated in this March) won the oral presentation award at the 97th CSJ annual meeting. Congrats!
Mar, 2017:
Mr. Kojima’s paper regarding macrocyclic peptides inhibiting a histone demethylase has been published in Nature Communications!→link
Mar, 2017:
Dr. Yu’s paper regarding macrocyclic peptides inhibiting a glycosidase has been published in Nature Communications!→link
Mar, 2017:
Associate Professor Goto won the CSJ Award for Young Chemists. Congrats!
Mar, 2017:
Dr. Jongkees's paper regarding macrocyclic peptides inhibiting a phosphoglycerate mutase has been published in Cell Chemical Biology!→link
Feb, 2017:
Associate Professor Goto's paper regarding in vitro biosynthesis of goadsporin (collaboration with Prof. Onaka) has been published in Nature Communications!→link. See here for the press release.
Jan, 2017:
Assistant Professor Katoh's paper regarding consecutive elongation of D-amino acids in translation has been published in Cell Chemical Biology→link We also added one review paper into the publication list.
Dec, 2016:
Dr. Terasaka's paper regarding a microRNA precursor binding to folic acidhas been published in RNA!→link
Nov, 2016:
Dr. Bashiruddin's paper regarding allosteric Inhibitors of Plexin B1 has been published in Cell Chemical Biology!→link We also added five other papers into the publication list.
Nov, 2016:
Professor Suga was awarded the Special Award in Japan Inovator Award 2016. Congratulations!!→link
Nov, 2016:
Dr. Jongkees's paper regarding ribosomnal synthesis of macrocyclic peptides bearing carbohydrates has been published in Chemical Science!→link
Oct, 2016:
Associate Professor Goto won the Young Investigator Award from the Japanese Peptide Society. Congrats!
Oct, 2016:
Mr. Yoshikane (M2) won the poster presentation award at the 53rd Japanese Peptide Symposium. Congrats!
Oct, 2016:
Professor Suga won the Max Bergmann-Medal! Congrats!!
Oct, 2016:
Associate Professor Goto's paper regarding substrate tolerance of PatD has been published in Chemistry Letters. This paper has been highlighted as Editor's Choice→link
Sep, 2016:
Dr. Yin won the JSPS fellowship. Congrats!
Aug, 2016:
We won the Best Crazy Award (1st prize in the lab introduction section) at the 48th Peptide Summer School! → pic
Aug, 2016:
Mr. Otero (M2) won the Excellent Poster Award at the 48th Peptide Summer School. Congrats! → pic
July, 2016:
Suga Lab won a victory at the softball tournament of the faculty!→ pic
Jul, 2016:
Mr. Iwane (D3) won won the poster award in "創薬懇話会2016 (drug development meeting 2016)". Congrats!
June, 2016:
Mr. Iwane (D3) won the best award in "第30回 独創性を拓く 先端技術大賞" (the 30th advanced technology award). Congrats!
May, 2016:
Mr. Nishio (D3) won the oral presentation award at the 96th CSJ annual meeting. Congrats!
May, 2016:
Assistant Professor Katoh's paper regarding essential structural elements in tRNAPro for EF-P recognition has been published in Nature Communications→link
May, 2016:
Dr. Futai's paper regarding a tRNA-removal methodology has been published in Methods!→link
Apr, 2016:
Dr. Hirose, Dr. Maini, Mr. Ishida, and Mr. Ozawa won JSPS fellowship. Congrats!
Apr, 2016:
We welcomed eight new members the lab!
Mar, 2016:
Mr. Ishida and Mr. Takeue won the scholar of excellence award from Graduate school of Science and Department of Chemistry, respectively. Congrats!
Mar, 2016:
Three members graduated from the lab.
Mar, 2016:
Professor Suga won the Gold Medal Award from the Yomiuri Techno Forum! Congrats!!→link
Mar, 2016:
Mr. Yasuharu Kato's presentation planned at the 96th CSJ annual meeting was selected as a Highlight Presentation! This topic has been reported in the Nikkei Biotech.→link
Feb, 2016:
Mr. Iwane's paper regarding artificial division of codon boxes has been published in Nature Chemistry!→link We also added two other papers into the publication list.
Jan, 2016
Assistant Professor Goto won the Excellent Poster Award in the 8th Takeda Science Foundation Symposium on PharmaSciences!
Dec, 2015:
Dr. Iwasaki's paper regarding fluorescent peptidic probe of EpCAM has been published in the in vitro selection special issue of Journal of Molecular Evolution!→link. We also added two other papers into the publication list.
Sep, 2015:
Dr. Obexer won the JSPS fellowship. Congrats!
Aug, 2015:
Drs. Bashiruddin and Nagano's paper regarding expression of tricyclic peptides has been published in Bioorganic Chemistry!→link. We also added three other papers into the publication list.
Aug, 2015:
Mr. Yoshikane (M1) won the poster presentation award at the 47th Young Investigators' Summer School of Peptide Chemistry. Congrats!
Apr, 2015:
Professor Suga won the Prize for Science and Technology by the Minister! Congrats!→link
Apr, 2015:
Mr. Kato won JSPS fellowship. Congrats!
Apr, 2015:
We welcomed eleven new members the lab!
Mar, 2015:
Dr. Terasaka and Mr. Yoshikane won the scholar of excellence award from Graduate school of Science and Department of Chemistry, respectively.
Mar, 2015:
Eight members graduated from the lab.
Mar, 2015:
Dr. Ito's paper regarding artificial agonist of cMet has been published in Nature Communications!→link
Oct, 2014:
Professor Suga won the Akabori Memorial Award 2014!→link
Oct, 2014:
Mr. Ishida (M1) and Mr. Ozawa (M2) won ALPS scholarship and MERIT scholarship, respectively.
Sep, 2014:
Mr. Terasaka (D3) won the Sidney Altman Endowment Travel Award at the 25th tRNA conference! Congrats!
Aug, 2014:
Mr. Ishida (M1) and Mr. Nishio (D1) won the oral presentation award and poster presentation award, respectively, at the 46th Young Investigators' Summer School of Peptide Chemistry. Congrats!
Jul, 2014:
Mr.Yoshikane (B4) won the ICE Seminar Best Poster award at 6th AEC, BAEC-I&II Summer ICE Seminar!
May, 2014:
Mr. Terasaka and Dr. Hayashi's paper regarding orthogonal ribosome has been published in Nature Chemical Biology!→link. See here for the press release.
May, 2014:
Ms. Ito and Dr. Goto's paper regarding one-pot biosynthesis of azoline-containing peptides has been published in Chemistry & Biology!→link
Apr, 2014:
Dr. Loik, Mr. Iwane, Mr. Nishio, and Mr. Kato won fellowships. Congrats!
Apr, 2014:
Dr. Passioura has been promoted to assistant professor!
Apr, 2014:
We welcomed five new members the lab!
Mar, 2014:
Eight students graduated from the lab.
Good luck on their future careers!
Dec, 2013:
Suga Lab won a victory at the football tournament of the faculty!→link for a picture
Nov, 2013
Mr. Yamaguchi (D1) won the poster presentation award at the 3rd CSJ Chemistry Festa!
Nov, 2013
Assistant Professor Goto won the Excellent Stone Award in APIPS2013!
Oct, 2013
Mr. Iwane (M2) and Mr. Ito (D3) won the poster presentation award at the 9th International Symposium on Aminoacyl-tRNA Synthetases (AARS2013). Congrats!
Oct, 2013
Our paper regarding reprogrammed dual sense codons has been published in ACS Chemical Biology!→link
Sep, 2013
Assistant Professor Goto won the Presentation Award in the Biofunctional Chemistry devision of CSJ!
Sep, 2013
Mr. Kimura (M1) and Ms. Song (M2) won MERIT scholarship and ALPS scholarship, respectively. Congrats!
Aug, 2013
Dr. Hipolito's paper regarding pfMATE-binding peptides has been published in Molecules!→link
Aug, 2013
Mr. Terasaka (D2) won the presentation award at the 15th Annual Meeting of the RNA Society of Japan. Congrats!
July, 2013
Mr. Yasuharu Kato (M2) and Mr. Ryo Takatsuji won the best oral presentation award and poster presentation award, respectively, at the 45th Young Investigators' Summer School of Peptide Chemistry. Congrats!
July, 2013
Assistant Professor Katoh won the Rising Star Award from Japan Science and Technology Agency!
July, 2013
Suga Lab won a victory at the softball tournament of the faculty!→link for pictures
May, 2013:
The first Suga lab alumni party: Over 80 former and current lab members celebrated the 10th anniversary of the Suga Lab at the University of Tokyo.→link for a picture
Apr, 2013:
Assistant Professor Goto won the CSJ Presentation Award in the 93rd Annual Meeting of the Chemical Society of Japan!
Apr, 2013:
Assistant Professor Goto won the Young Scientists Prize by the Minister of MEXT!
Apr, 2013:
Dr. Nagano and Dr. Yoshitomi won fellowships (PD) from the JSPS. Congrats!
Apr, 2013:
We welcomed eight new members the lab!
May, 2013:
Three Ph.D. students (Dr. Iida, Dr. Shimomai, Dr. Reza) graduated from the lab.
Good luck on their future careers!
Feb, 2013:
Professor Suga won the CSJ Award for Creative Work!→link
Feb, 2013:
Our paper has been accepted by Nature! It regards the Dr. Hipolito's work where crystal structures of pfMATE protein binding to new macrocyclic peptides were solved.
Jan, 2013:
Dr. Nagano (postdoc) won the Teijin Pharma Award in Synthetic Organic Chemistry. Congrats!
Dec, 2012:
Suga Lab won a victory at the football tournament of the faculty!→link for a picture
Sep, 2012:
Mr. Ito (D2 student) won a poster presentation award at the 27th forum for young researchers in biofunctional chemistry. Congrats!
Jan, 2012:
SciBX (Nature publishing group) featured our research regarding discovery of bioactive peptides powered by the RaPID system.→link
2012年6月:
M1の井関さんが6/8に開催された新規素材探索研究会第11回セミナーにおいて、新規素材探索奨励賞を受賞しました。おめでとう!
2012年5月:
ポスドクの林さん・柴田さんが菅研を巣立っていきました。
新しい職場での活躍を願っています!
2012年4月:
3月に行われた日本化学会において、森本君が学生講演賞を受賞しました。おめでとう!
2012年4月:
林剛介さんが日本学術振興会の海外特別研究員採用されました!アメリカでの素晴らしい研究成果を期待しています。
2012年4月:
藤田さんが日本学術振興会の特別研究員(PD)に、寺坂君が特別研究員(DC1)にそれぞれ採用されました!
2012年4月:
今年度の新メンバーが加入しました。ポスドク2人・博士課程1人・修士課程4人・学部生4人が加わり、また賑やかになります!
2012年3月:
ポスドクの二井さん・Mengさん、博士課程の五十嵐さん・岩崎君・森本君、修士課程の伊藤さんが無事研究室を巣立っていきました!
長い間どうもありがとうございました。これからも新天地で頑張って下さい。
2012年3月:
日本化学会第92春季年会のATPセッションにおいて、森本君が注目ポスター賞を受賞しました。おめでとう!
2012年3月:
D3岩崎君の翻訳ペプチドのチオエーテル環化の論文がOrganic & Biomolecular Chemistryに掲載決定!
OBCの10周年記念号に掲載予定です。 →リンク
"Selective thioether macrocyclization of peptides having the N-terminal 2-chloroacetyl group and competing two or three cysteine residues in translation"
2012年2月:
D3森本君のsirtuinの阻害剤の論文がAngewandte Chemie International Editionに掲載決定! →リンク
"Discovery of Macrocyclic Peptides Armed with a Mechanism-Based Warhead: Isoform-Selective Inhibition of Human Deacetylase SIRT2"
2012年2月:
卒業生の進路に関するページを追加しました。→リンク
2012年1月:
選択的Akt2阻害ペプチドの論文がACS Chemical Biologyに掲載決定! →リンク
"In Vitro Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform-Selective Inhibitors" …林勇樹
2011年12月:
後藤助教の研究課題がJST戦略的創造研究推進事業(さきがけ)「細胞機能の構成的な理解と制御」領域に採択されました!
『人工二次代謝産物』の創成を目指して研究を推進していきます。→リンク
2011年11月:
特殊ペプチドの試験管内人工進化の論文がChemistry&Biology誌に掲載決定! →12月号に掲載
"Natural product-like macrocyclic N-methyl-peptide inhibitors against a ubiquitin ligase uncovered from a ribosome-expressed de novo library" …山岸祐介
Nature publishing groupのSciBXからインタビューを受けました。近日中に記事が掲載されます。
2011年11月:
岩根君が全国国公立大学空手道選手権大会にて団体優勝!
優秀選手賞も受賞したそうです。おめでとう!
2011年11月:
Hipolitoさんが日本学術振興会の外国人特別研究員に採用されました!
2011年9月:
菅教授が産学官連携功労者表彰 日本学術会議会長賞を受賞しました! →リンク
"創薬プラットフォーム技術「RAPIDシステム」の実用化"…ぺプチドリーム株式会社との共同受賞
2011年8月:
Proc. Natl. Acad. Sci. USA誌に論文掲載決定! →リンク
"Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum" …樋口岳、von Heijne研との共同研究
2011年5月:
Nature Protocols に掲載決定! →リンク
"Flexizymes for genetic code reprogramming" …後藤佑樹、加藤敬行
2011年5月:
ChemBioChem に掲載決定! →リンク
"Ribosomal Synthesis of Backbone-Macrocyclic Peptides Containing γ-Amino Acids" …大城幸紀、中島永二、後藤佑樹
表紙にも選ばれました!
2011年4月:
伊藤君が日本学術振興会の特別研究員(DC1)に採用されました!
2011年1月:
Angewandte Chemie International Edition に掲載決定! →リンク
"Synthesis of the Backbone Cyclic Peptide Sunflower Trypsin Inhibitor-1 Promoted by the Induced Peptidyl-tRNA Drop-off" …T.-J. Kang、林勇樹
2010年12月:
第五回国際ペプチドシンポジウム in 京都
オーラルプレゼン賞受賞…山岸祐介(3年連続で菅研獲得!)
ポスター賞受賞…林勇樹、大城幸紀、森本淳平の3人が受賞
2010年9月:
日本化学会生体機能関連化学部会 第25回若手フォーラム ポスター賞受賞…森本淳平